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餐后不适综合征的胃排空闪烁扫描

Gastric emptying scintigraphy in postprandial distress syndrome.

作者信息

Hafeez Muhammad, Hussain Fida, Salamat Amjad, Khan Muhammad Bilal

机构信息

Dr. Muhammad Hafeez, Consultant Physician & Gastroenterologist, Combined Military Hospital Multan Pakistan.

Dr. Fida Hussain, Department of Nuclear Medicine, Armed Forces Institute of Pathology Rawalpindi Pakistan.

出版信息

Pak J Med Sci. 2018 Jan-Feb;34(1):27-31. doi: 10.12669/pjms.341.14137.

DOI:10.12669/pjms.341.14137
PMID:29643873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5857022/
Abstract

OBJECTIVE

To find out the pattern of gastric emptying scintigraphy (GES) in patients with post prandial distress syndrome (PDS).

METHODS

This study was carried out from January 2015 to July 2016 at Combined Military Hospital (CMH) Kharian and Nuclear Medical Centre (NMC) of Armed Forces Institute of Pathology (AFIP) Rawalpindi. Patient's inclusion criteria were dyspepsia of post prandial distress type for more than six months duration. Patients with dyspepsia due to epigastric pain syndrome and other organic disorder were excluded. Upper gastrointestinal endoscopy was performed in all patients to rules out organic causes. Four-hour Gastric emptying scintigraphy was carried out at NMC, AFIP. Results were compiled and statistical assessment was done by utilizing SPSS IBM 22 version.

RESULTS

Thirty-eight patients were included in the study with age range from 15-72 years with mean age of 37.05±13.5 years. Males were 28(73.7%) and 10(26.7%) were female. Mean gastric retention with SD at one, two, three and four hours were 63 ± 19.04, 37± 20.62, 19±16.66 and 10±12.73 percent respectively. Early gastric emptying was in 3(7.89%) and delayed gastric emptying at two and four hours was seen in 4(10.52%) and 12(32%) respectively. Seventeen (44%) of the patients had normal gastric emptying despite the classical symptoms of PDS.

CONCLUSION

Gastric dysmotility in GES seen in half of the patients points some additional mechanism as well like gastric accommodation or visceral hypersensitivity in the patients with PDS.

摘要

目的

探究餐后不适综合征(PDS)患者的胃排空闪烁扫描(GES)模式。

方法

本研究于2015年1月至2016年7月在哈里安联合军事医院(CMH)以及拉瓦尔品第武装部队病理研究所(AFIP)的核医学中心(NMC)开展。患者纳入标准为餐后不适型消化不良持续时间超过6个月。排除因上腹部疼痛综合征和其他器质性疾病导致消化不良的患者。所有患者均接受上消化道内镜检查以排除器质性病因。在AFIP的NMC进行4小时胃排空闪烁扫描。收集结果并使用IBM SPSS 22版本进行统计评估。

结果

38例患者纳入研究,年龄范围为15 - 72岁,平均年龄为37.05±13.5岁。男性28例(73.7%),女性10例(26.7%)。1小时、2小时、3小时和4小时的平均胃潴留及标准差分别为63±19.04%、37±20.62%、19±16.66%和10±12.73%。早期胃排空的有3例(7.89%),2小时和4小时胃排空延迟的分别有4例(10.52%)和12例(32%)。17例(44%)患者尽管有PDS的典型症状,但胃排空正常。

结论

在一半的患者中观察到GES存在胃动力障碍,这表明PDS患者还存在一些其他机制,如胃容受性或内脏高敏感性。

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Am J Gastroenterol. 2017 Jan;112(1):132-140. doi: 10.1038/ajg.2016.499. Epub 2016 Dec 13.
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Fasting and postprandial gastric sensorimotor activity in functional dyspepsia: postprandial distress vs. epigastric pain syndrome.功能性消化不良患者的空腹及餐后胃感觉运动活性:餐后不适综合征与上腹痛综合征
Am J Gastroenterol. 2014 Oct;109(10):1631-9. doi: 10.1038/ajg.2014.231. Epub 2014 Sep 9.
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