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七分钟筛查:一种对各类痴呆症高度敏感的神经认知筛查测试。

The seven minute screen: a neurocognitive screening test highly sensitive to various types of dementia.

作者信息

Meulen E F J, Schmand B, van Campen J P, de Koning S J, Ponds R W, Scheltens P, Verhey F R

机构信息

Department of Clinical Geriatrics and Medical Psychology, General Hospital Slotervaart, Slotervaart, Netherlands.

出版信息

J Neurol Neurosurg Psychiatry. 2004 May;75(5):700-5. doi: 10.1136/jnnp.2003.021055.

Abstract

BACKGROUND

The seven minute screen (7MS) is a compilation of the temporal orientation test, enhanced cued recall, clock drawing, and verbal fluency. It has been shown to be useful for detecting Alzheimer's disease in a population of patients with memory complaints.

OBJECTIVE

To assess the predictive validity of the 7MS for various types of dementia, and the influence of depression and other psychiatric conditions on 7MS scores.

SETTING

Multicentre: secondary referral sites across the Netherlands.

SUBJECTS

542 patients with various types of dementia or depression, together with 45 healthy controls.

RESULTS

Alzheimer's disease was diagnosed in 177 patients, other types of dementia in 164. The sensitivity of the 7MS for Alzheimer's disease was 92.9% with a specificity of 93.5%. For other types of dementia the sensitivity was 89.4% and the specificity 93.5%. Cognitive abnormalities were found in 71% of the patients with depression (n = 31). The mean (SD) duration of administration of the 7MS was 12.4 (4.6) minutes, range 8 to 22, depending on dementia severity.

CONCLUSIONS

The 7MS is a useful screening tool for discriminating patients with dementia from cognitively intact patients. This not only applies to Alzheimer's disease but also to other types of dementia. Specificity with respect to depression was lower for the 7MS than for the MMSE.

摘要

背景

七分钟筛查量表(7MS)由时间定向测试、强化线索回忆、画钟测试和语言流畅性测试组成。研究表明,它对于在有记忆障碍主诉的患者群体中检测阿尔茨海默病很有用。

目的

评估7MS对各类痴呆的预测效度,以及抑郁和其他精神状况对7MS评分的影响。

设置

多中心:荷兰各地的二级转诊机构。

受试者

542例患有各类痴呆或抑郁症的患者,以及45名健康对照者。

结果

177例患者被诊断为阿尔茨海默病,164例为其他类型痴呆。7MS对阿尔茨海默病的敏感性为92.9%,特异性为93.5%。对其他类型痴呆,敏感性为89.4%,特异性为93.5%。71%的抑郁症患者(n = 31)存在认知异常。7MS的平均(标准差)施测时长为12.4(4.6)分钟,范围为8至22分钟,取决于痴呆严重程度。

结论

7MS是一种用于区分痴呆患者和认知功能正常患者的有用筛查工具。这不仅适用于阿尔茨海默病,也适用于其他类型痴呆。7MS对抑郁症的特异性低于简易精神状态检查表(MMSE)。

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