Kim Mi Young, Suh Chang Hae, Kim Sang Tae, Lee Jung Hee, Kong Kyungup, Lim Tae-Hwan, Suh Jeong Soo
Department of Radiology, Inha University College of Medicine, Inha University Hospital, Incheon City, Korea.
J Comput Assist Tomogr. 2004 Mar-Apr;28(2):187-92. doi: 10.1097/00004728-200403000-00006.
To assess the usefulness of magnetic resonance (MR) imaging for detecting bowel ischemia with strangulation compared with histopathologic findings in an experimental cat model.
Fourteen cats were assigned to the normal control group (n = 3), acute ischemic group (induced by ligation of superior mesenteric vessels for 3 hours, n = 7), and subacute ischemic group (induced by ligation of superior mesenteric vessels for 10 hours, n = 4). Using a 4.7-T MR scanner, contrast-enhanced T1-weighted images were obtained at 0, 10, 20, 30, and 60 minutes after bolus injection of contrast media. T1- and T2-weighted images were obtained from the extracted bowel wall and compared with histopathologic findings.
On contrast-enhanced MR images, the target-like bowel wall layers were clearly demonstrated and the submucosal layer showed the most prominent enhancement. At 10 minutes after administration of contrast media, the subacute ischemic group showed significantly lower enhancement of the submucosal layer than the normal or acute ischemic group (P <0.05). On T1-weighted images, there were not significant differences between the normal and ischemic bowel groups (P >0.05). On T2-weighted images, the signal intensity of all layers of acute ischemic bowel wall was significantly higher than that of the normal control or subacute ischemic group (P <0.05).
Delayed contrast-enhanced MR images and T2-weighted images were helpful for detecting subacute and acute bowel ischemia with strangulation, respectively.
在实验性猫模型中，将磁共振（MR）成像用于检测绞窄性肠缺血的效用与组织病理学结果进行比较评估。
14只猫被分配至正常对照组（n = 3）、急性缺血组（通过结扎肠系膜上血管3小时诱导，n = 7）和亚急性缺血组（通过结扎肠系膜上血管10小时诱导，n = 4）。使用4.7-T MR扫描仪，在静脉注射造影剂后0、10、20、30和60分钟获取对比增强T1加权图像。从提取的肠壁获取T1加权和T2加权图像，并与组织病理学结果进行比较。
在对比增强MR图像上，可见靶样肠壁层，黏膜下层显示出最显著的强化。在注射造影剂后10分钟，亚急性缺血组黏膜下层的强化明显低于正常组或急性缺血组（P <0.05）。在T1加权图像上，正常肠组和缺血肠组之间无显著差异（P >0.05）。在T2加权图像上，急性缺血肠壁各层的信号强度显著高于正常对照组或亚急性缺血组（P <0.05）。
延迟对比增强MR图像和T2加权图像分别有助于检测亚急性和急性绞窄性肠缺血。
