Gupta D K, Charles A R, Srinivas M
Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India.
Pediatr Surg Int. 2004 Jun;20(6):415-8. doi: 10.1007/s00383-004-1166-y. Epub 2004 Apr 17.
Gastric transposition (GT) is one of the options for the esophageal replacement in children with esophageal atresia with or without tracheoesophageal fistula (EATEF). To date, no manometric studies have been conducted on the intrathoracic stomach after GT in EATEF patients; hence, this study was designed. Babies ( n=18) of EATEF who underwent esophageal replacement by GT were studied and manometry was correlated with the clinical outcome, age at surgery, and route of GT. The mean age at evaluation was 30.5 months (range 4-84 months). These cases were sub-stratified into group I (GT during neonatal period) and group II (GT during post-neonatal period). Mean age at surgery was 6 days and 7.8 months in groups I and II, respectively. There was no propulsive antegrade propagated peristaltic waves in any of the patients. Mean resting pressure and mean peak pressures were 19.5 and 50.4 mm Hg in groups I and II, respectively. Mass contractions to liquid swallow was noted in 77 and 55% of patients in groups I and II, respectively. There was no significant difference in the pressure parameters or appearance of mass contractions between group-I and group-II patients. Similarly, there was no significant difference in pressure parameters or appearance of mass contractions between the children who had transhiatal vs retrosternal GT. It needs to be determined whether the mass contractions noted in GT ever progress to a coordinated propulsive rhythmic contractions and whether this has a final bearing on the long-term functional outcome of GT patients.
胃转位术(GT)是食管闭锁合并或不合并气管食管瘘(EATEF)患儿食管替代的选择之一。迄今为止,尚未对EATEF患者行GT术后胸腔内胃进行测压研究;因此,开展了本研究。对18例接受GT食管替代术的EATEF患儿进行研究,并将测压结果与临床结局、手术年龄和GT路径相关联。评估时的平均年龄为30.5个月(范围4 - 84个月)。这些病例被分为I组(新生儿期行GT)和II组(新生儿期后行GT)。I组和II组的平均手术年龄分别为6天和7.8个月。所有患者均未出现推进性顺行传播蠕动波。I组和II组的平均静息压力分别为19.5和50.4 mmHg,平均峰值压力分别为19.5和50.4 mmHg。I组和II组分别有77%和55%的患者出现对液体吞咽的集团性收缩。I组和II组患者之间的压力参数或集团性收缩表现无显著差异。同样,经裂孔GT与胸骨后GT患儿之间的压力参数或集团性收缩表现也无显著差异。需要确定GT中观察到的集团性收缩是否会发展为协调性推进性节律性收缩,以及这是否最终影响GT患者的长期功能结局。