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伴有多肌炎的抗PM-SCL自身抗体阳性硬皮病(技工手:诊断的临床辅助依据)

PM-SCL autoantibody positive scleroderma with polymyositis (mechanic's hand: clinical aid in the diagnosis).

作者信息

Török L, Dankó K, Cserni G, Szûcs G

机构信息

Department of Dermatology, County Hospital of Bács-Kiskun (Kecskemét), 6000 Kecskemét, Nagykörösi u 15, Hungary.

出版信息

J Eur Acad Dermatol Venereol. 2004 May;18(3):356-9. doi: 10.1111/j.1468-3083.2004.00868.x.

Abstract

This report concerns a 56-year-old-woman presenting PM-SCL autoantibody positive scleroderma with dermatomyositis (scleromyositis) and concomitant interstitial lung fibrosis. The recently observed overlapping syndrome is characterized by the presence of specific autoantibodies, HLA-type association and benign course. A new skin symptom ("mechanic's hands") predicts the disease, in particular the interstitial lung pathology, which is its most relevant internal manifestation.

摘要

本报告涉及一名56岁女性,其抗PM - SCL自身抗体阳性,患有硬皮病合并皮肌炎(硬皮肌炎)及间质性肺纤维化。最近观察到的重叠综合征的特征为存在特异性自身抗体、HLA型关联及良性病程。一种新的皮肤症状(“技工手”)可预测该病,尤其是间质性肺病变,这是其最相关的内脏表现。

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