Department of Dermatology and Section of Allergy and Rheumatology, St. Luke's International Hospital, Tokyo, Japan.
Int J Dermatol. 2009 Nov;48(11):1177-82. doi: 10.1111/j.1365-4632.2009.04164.x.
Mechanic's hand is a defined specific skin eruption associated with dermatomyositis; there are few reports concerning its histopathology. As mechanic's hand clinically resembles hand eczema, it is important to distinguish between these two conditions.
To determine the characteristic clinical and histopathologic features of mechanic's hand, and to clarify whether these two conditions can be differentiated by histopathologic findings.
We analyzed clinicopathologically five patients with mechanic's hands who visited our clinic between 2006 and 2007.
The clinical features of mechanic's hands were discrete hyperkeratotic erythema on the ulnar aspect of the thumbs and the radial aspect of the fingers. In all five cases, the histologic findings included marked hyperkeratosis, focal parakeratosis, psoriasiform acanthosis, and colloid bodies in the epidermis. There were mononuclear cell infiltrates around the blood vessels, and mucin deposition was observed in the dermis.
The histopathologic findings of mechanic's hands are specific and different from those of eczema. A histopathologic examination is useful for the diagnosis of mechanic's hands associated with dermatomyositis and a high incidence of interstitial pneumonia.
技工手是一种与皮肌炎相关的特定皮肤疹，其组织病理学少有报道。由于技工手在临床上类似于手部湿疹，因此区分这两种情况很重要。
确定技工手的特征性临床和组织病理学特征，并阐明这些两种情况是否可以通过组织病理学发现来区分。
我们分析了 2006 年至 2007 年间在我院就诊的五例技工手患者的临床病理资料。
技工手的临床特征为拇指尺侧和手指桡侧的离散性角化过度性红斑。在所有五例中，组织学发现包括表皮显著角化过度、局灶性角化不全、银屑病样棘层肥厚和胶样小体。血管周围有单核细胞浸润，真皮内可见黏蛋白沉积。
技工手的组织病理学发现是特异的，与湿疹不同。组织病理学检查对皮肌炎相关的技工手和间质性肺炎高发的诊断很有帮助。
