Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania; Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Section of Dermatology, Department of Medicine, University of the Philippines-Philippine General Hospital, Manila, Philippines.
Department of Dermatology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
J Am Acad Dermatol. 2018 Apr;78(4):769-775.e2. doi: 10.1016/j.jaad.2017.10.034. Epub 2017 Nov 2.
Mechanic's hands is a poorly defined clinical finding that has been reported in a variety of rheumatologic diseases. Morphologic descriptions include hyperkeratosis on the sides of the digits that sometimes extends to the distal tips, diffuse palmar scale, and (more recently observed) linear discrete scaly papules in a similar lateral distribution. The association of mechanic's hands with dermatomyositis, although recognized, is still debatable. In this review, most studies have shown that mechanic's hands is commonly associated with dermatomyositis and displays histopathologic findings of interface dermatitis, colloid bodies, and interstitial mucin, which are consistent with a cutaneous connective tissue disease. A more specific definition of this entity would help to determine its usefulness in classifying and clinically identifying patients with dermatomyositis, with implications related to subsequent screening for associated comorbidities in this setting.
技工手是一种定义不明确的临床发现，已在多种风湿性疾病中报道。形态学描述包括指尖侧的过度角化，有时延伸至远端，弥漫性掌部鳞屑，以及（最近观察到的）类似侧分布的线性离散鳞屑丘疹。技工手与皮肌炎的关联虽然已被认识到，但仍存在争议。在这篇综述中，大多数研究表明，技工手通常与皮肌炎相关，并表现出界面性皮炎、胶样小体和间质粘蛋白的组织病理学发现，这与皮肤结缔组织疾病一致。对这一实体的更具体定义将有助于确定其在皮肌炎分类和临床识别患者中的有用性，并对该环境中相关合并症的后续筛查产生影响。
