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童年期心理能力与中年期血压:连接1932年苏格兰心理调查和中年期研究

Childhood mental ability and blood pressure at midlife: linking the Scottish Mental Survey 1932 and the Midspan studies.

作者信息

Starr John M, Taylor Michelle D, Hart Carole L, Davey Smith George, Whalley Lawrence J, Hole David J, Wilson Valerie, Deary Ian J

机构信息

Royal Victoria Hospital, Craigleith Road, Edinburgh EH4 2DN, Scotland, UK.

出版信息

J Hypertens. 2004 May;22(5):893-7. doi: 10.1097/00004872-200405000-00009.

DOI:10.1097/00004872-200405000-00009
PMID:15097227
Abstract

OBJECTIVES

To establish the relationship between childhood mental ability and adult hypertension.

DESIGN

Retrospective cohort study.

SETTING

Community.

PARTICIPANTS

Non-clinical sample of people born in 1921 who participated in both the Scottish Mental Survey 1932 and the Midspan studies. Nine hundred and thirty-eight people were participants in both studies.

MAIN OUTCOME MEASURES

Mid-life systolic and diastolic blood pressure, intelligence quotient (IQ) at age 11 years, sex, social class, height and weight.

RESULTS

After adjustment for age, sex, social class, body mass index, height, cholesterol level and smoking, there remained a 3.15 mmHg decrease in systolic blood pressure and a 1.5 mmHg decrease in diastolic blood pressure for each standard deviation increase in childhood IQ.

CONCLUSIONS

The association between hypertension and lower cognitive function in adulthood is partly accounted for by individual differences in childhood IQ.

摘要

目的

建立儿童心理能力与成人高血压之间的关系。

设计

回顾性队列研究。

地点

社区。

参与者

1921年出生、参加了1932年苏格兰心理调查和中年期研究的非临床样本。938人同时参与了这两项研究。

主要观察指标

中年时的收缩压和舒张压、11岁时的智商(IQ)、性别、社会阶层、身高和体重。

结果

在对年龄、性别、社会阶层、体重指数、身高、胆固醇水平和吸烟情况进行校正后,儿童期智商每增加一个标准差,收缩压仍会降低3.15 mmHg,舒张压降低1.5 mmHg。

结论

成年期高血压与较低认知功能之间的关联部分可由儿童期智商的个体差异来解释。

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