关于儿童智商与76岁前生存率的纵向队列研究。
Longitudinal cohort study of childhood IQ and survival up to age 76.
作者信息
Whalley L J, Deary I J
机构信息
Department of Mental Health, University of Aberdeen, Clinical Research Centre, Cornhill Hospital, Aberdeen AB24 2ZD.
出版信息
BMJ. 2001 Apr 7;322(7290):819. doi: 10.1136/bmj.322.7290.819.
Abstract
OBJECTIVES
To test the association between childhood IQ and mortality over the normal human lifespan.
DESIGN
Longitudinal cohort study.
SETTING
Aberdeen.
SUBJECTS
All 2792 children in Aberdeen born in 1921 and attending school on 1 June 1932 who sat a mental ability test as part of the Scottish mental survey 1932.
MAIN OUTCOME MEASURE
Survival at 1 January 1997.
RESULTS
79.9% (2230) of the sample was traced. Childhood mental ability was positively related to survival to age 76 years in women (P<0.0001) and men (P<0.0001). A 15 point disadvantage in mental ability at age 11 conferred a relative risk of 0.79 of being alive 65 years later (95% confidence interval 0.75 to 0.84); a 30 point disadvantage reduced this to 0.63 (0.56 to 0.71). However, men who died during active service in the second world war had a relatively high IQ. Overcrowding in the school catchment area was weakly related to death. Controlling for this factor did not alter the association between mental ability and mortality.
CONCLUSION
Childhood mental ability is a significant factor among the variables that predict age at death.
摘要
目的
检验儿童期智商与正常人类寿命期间死亡率之间的关联。
设计
纵向队列研究。
地点
阿伯丁。
研究对象
1921年出生于阿伯丁且在1932年6月1日上学的所有2792名儿童，他们参加了作为1932年苏格兰智力调查一部分的智力测试。
主要观察指标
1997年1月1日的生存情况。
结果
79.9%（2230名）的样本被追踪到。儿童期智力与女性（P<0.0001）和男性（P<0.0001）活到76岁的生存率呈正相关。11岁时智力低15分，65年后存活的相对风险为0.79（95%置信区间0.75至0.84）；低30分则降至0.63（0.56至0.71）。然而，在第二次世界大战中服现役期间死亡的男性智商相对较高。学校招生区域的拥挤程度与死亡的关联较弱。控制该因素并未改变智力与死亡率之间的关联。
结论
儿童期智力是预测死亡年龄的变量中的一个重要因素。
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