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[人类淋巴细胞中不稳定染色体畸变频率的生物学指征及剂量测定]

[Biological indication and dosimetry of unstable chromosome aberration frequencies in human lymphocytes].

作者信息

Baryliak I R, D'omina E A

出版信息

Tsitol Genet. 2004 Jan-Feb;38(1):72-85.

Abstract

Review is devoted to the problems of biological (cytogenetic) dosimetry and indication of degree of radiation lesions based on analysis of unstable chromosome aberrations in lymphocytes of human peripheral blood. Effects of radiation in low doses on human chromosomes and methodology of interpretation of the character of dose cytogenetic curves are discussed. Traditional cytogenetic analysis remains the basic one for monitoring in groups of people with accidental irradiation.

摘要

综述致力于生物(细胞遗传学)剂量测定问题以及基于对人外周血淋巴细胞中不稳定染色体畸变的分析来指示辐射损伤程度。讨论了低剂量辐射对人类染色体的影响以及剂量细胞遗传学曲线特征的解释方法。传统的细胞遗传学分析仍然是对意外受照人群进行监测的基本方法。

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