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[贻贝聚糖(来自灰裂肌蛤的一种生物聚糖)对实验性流感感染病程及结果的影响]

[Effect of mytilane, a bioglycan from the mussel Crenomytilus grayanus, on the course and outcome of experimental flu infection].

作者信息

Tsybul'skiĭ A V, Isachkova L M, Ovodova R G, Glazkova V E, Besednova N N, Orlova T G

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1992 Mar(3):62-6.

PMID:1509854
Abstract

Materials characterizing the antiviral activity of Mytilane, manifested by the protection of 50-60% of mice infected with the lethal dose of influenza virus and by a decrease in the severity of pathological changes in the lungs of mice, are presented. The inhibiting activity of Mytilane with respect to the reproduction of influenza virus in vivo and in vitro under experimental conditions is demonstrated.

摘要

本文展示了表征米蒂兰抗病毒活性的材料,其表现为可保护50%至60%感染致死剂量流感病毒的小鼠,并减轻小鼠肺部病理变化的严重程度。实验条件下,米蒂兰在体内和体外对流感病毒复制的抑制活性得到了证实。

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