Geijer Håkan, Persliden Jan
Department of Radiology, Orebro University Hospital, 701 85 Orebro, Sweden.
Eur Radiol. 2004 Sep;14(9):1674-80. doi: 10.1007/s00330-004-2322-4. Epub 2004 Apr 21.
The aim of this study was to evaluate radiation dose and patient discomfort/pain in radial artery access vs femoral artery access in percutaneous coronary intervention (PCI). Dose-area product (DAP) was measured non-randomised for 114 procedures using femoral access and for 55 using radial access. The patients also responded to a questionnaire concerning discomfort and pain during and after the procedure. The mean DAP was 69.8 Gy cm(2) using femoral access and 70.5 Gy cm(2) using radial access. Separating the access site from confounding factors with a multiple regression, there was a 13% reduction in DAP when using radial access (p=0.038). Procedure times did not differ (p=0.81). Bed confinement was much longer in the femoral access group (448 vs 76 min, p=0.000). With femoral access, there was a significantly higher patient grading for chest (p=0.001) and back pain (p=0.003) during the procedure and for access site (p=0.000) and back pain (p=0.000) after the procedure. Thirty-two femoral access patients (28%) were given morphine-type analgesics in the post-procedure period compared to three radial access patients (5%, p=0.001). DAP does not increase when using radial instead of femoral access and the patients grade discomfort and pain much lower when using radial access. Radial access is thus beneficial to use.
本研究旨在评估经皮冠状动脉介入治疗(PCI)中经桡动脉入路与经股动脉入路的辐射剂量以及患者的不适/疼痛情况。对114例采用股动脉入路的手术和55例采用桡动脉入路的手术进行了非随机的剂量面积乘积(DAP)测量。患者还对有关手术期间及术后不适和疼痛的问卷做出了回应。采用股动脉入路时平均DAP为69.8 Gy cm²,采用桡动脉入路时为70.5 Gy cm²。通过多元回归将入路部位与混杂因素分开后,采用桡动脉入路时DAP降低了13%(p = 0.038)。手术时间无差异(p = 0.81)。股动脉入路组的卧床限制时间长得多(448分钟对76分钟,p = 0.000)。采用股动脉入路时,手术期间患者胸部(p = 0.001)和背部疼痛(p = 0.003)以及术后穿刺部位(p = 0.000)和背部疼痛(p = 0.000)的分级明显更高。术后有32例股动脉入路患者(28%)使用了吗啡类镇痛药,而桡动脉入路患者有3例(5%,p = 0.001)。采用桡动脉入路而非股动脉入路时DAP并未增加,且患者使用桡动脉入路时不适和疼痛分级要低得多。因此,采用桡动脉入路是有益的。