Saijo Masayuki, Tang Qing, Shimayi Bawudong, Han Lei, Zhang Yuzhen, Asiguma Muer, Tianshu Dong, Maeda Akihiko, Kurane Ichiro, Morikawa Shigeru
Special Pathogens Laboratory, Department of Virology I, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
Jpn J Infect Dis. 2004 Apr;57(2):55-7.
The case of a child with Crimean-Congo hemorrhagic fever (CCHF) presumably infected with CCHF virus from her 27-year-old mother is described. The mother with CCHF was treated with ribavirin and did not present with any symptoms of obvious hemorrhage. The child developed fever on the 5th day after the mother's onset. The partial virus genome was amplified by RT-PCR, and nested PCR from the child and the genome sequence were identical to that from the mother, indicating possible transmission of the virus from mother to child. This case indicates the importance of preventive measures for in-house outbreaks of CCHF.
描述了一名疑似感染克里米亚-刚果出血热（CCHF）病毒的儿童病例，该病毒据推测来自其27岁的母亲。患有CCHF的母亲接受了利巴韦林治疗，未出现任何明显出血症状。孩子在母亲发病后第5天出现发热。通过RT-PCR扩增了部分病毒基因组，并且从孩子身上进行的巢式PCR及其基因组序列与母亲的相同，表明病毒可能从母亲传播给了孩子。该病例表明了针对CCHF院内暴发采取预防措施的重要性。
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