Glance Laurent G, Osler Turner M, Dick Andrew, Mukamel Dana
Department of Anesthesiology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 604, Rochester, New York 14642, USA.
J Trauma. 2004 Mar;56(3):682-90. doi: 10.1097/01.ta.0000053469.92142.40.
Regionalization of trauma care services aims to improve outcomes by limiting trauma care delivery to a select group of dedicated trauma centers. However, the evidence linking trauma center volume and outcome is not conclusive. The objective of this study was to examine the volume-mortality relation for patients with severe trauma in the National Trauma Databank.
This study was based on data for adult patients 18 years of age or older in the National Trauma Databank with an Injury Severity Score (ISS) of 15 or more who sustained either blunt or penetrating trauma. The main outcome measure was in-hospital survival as a function of trauma center volume. Logistic regression modeling was used to analyze the relation between survival and hospital volume for patients sustaining either severe blunt or severe penetrating trauma.
For the blunt trauma cohort, model diagnostics showed that the single highest-volume center was an outlier. After exclusion of the patients from this center, no association could be demonstrated between trauma volume and outcome (p = 0.465) for blunt trauma. A separate multivariate analysis of patients with penetrating trauma also could not demonstrate a significant volume-mortality association (p = 0.919). Both regression models exhibited excellent discrimination and acceptable calibration.
The findings of this study do not support the position that higher trauma center volumes are associated with improved survival. The implication of this study is that the hospital volume criteria established by the American College of Surgeons may need to be reexamined.
创伤护理服务的区域化旨在通过将创伤护理服务局限于特定的一组专门创伤中心来改善治疗结果。然而,将创伤中心的工作量与治疗结果联系起来的证据并不确凿。本研究的目的是在国家创伤数据库中研究严重创伤患者的工作量与死亡率之间的关系。
本研究基于国家创伤数据库中18岁及以上成年患者的数据,这些患者的损伤严重程度评分(ISS)为15或更高,遭受钝性或穿透性创伤。主要结局指标是作为创伤中心工作量函数的院内生存率。采用逻辑回归模型分析严重钝性创伤或严重穿透性创伤患者的生存率与医院工作量之间的关系。
对于钝性创伤队列,模型诊断显示工作量最高的单一中心是一个异常值。排除该中心的患者后,钝性创伤的创伤工作量与治疗结果之间未显示出相关性(p = 0.465)。对穿透性创伤患者进行的单独多变量分析也未显示出显著的工作量-死亡率相关性(p = 0.919)。两个回归模型均表现出出色的区分度和可接受的校准度。
本研究结果不支持更高的创伤中心工作量与提高生存率相关的观点。本研究的意义在于,美国外科医师学会制定的医院工作量标准可能需要重新审视。