Loeffler A, Lloyd D H, Bond R, Kim J Y, Pfeiffer D U
Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA.
Vet Rec. 2004 Apr 24;154(17):519-22. doi: 10.1136/vr.154.17.519.
The owners of 63 pruritic dogs were instructed to feed them a chicken hydrolysate diet exclusively for six weeks as part of diagnostic investigations into non-seasonal pruritus. Ectoparasitism and microbial infections were eliminated during the dietary trial. The dogs' skin lesions, gastrointestinal signs and frequency of defecation were assessed and scores for pruritus were assigned before they started the diet and before and after they resumed their original diet. An adverse food reaction was diagnosed if the pruritus resolved while they were on the diet, but recurred when they resumed their original food regimen. Seventeen of the 63 dogs were withdrawn from the trial, including four which found the diet unpalatable; however, its palatability was reported to be good or excellent in 48 of the dogs. An adverse food reaction alone was diagnosed in nine (19.6 per cent) of the 46 dogs and another nine had an adverse food reaction and atopy. There were gastrointestinal signs in six of the nine dogs with an adverse food reaction, which resolved on the trial diet but recurred when they resumed their original diet.
63只患瘙痒症犬的主人接到指示，作为对非季节性瘙痒症诊断调查的一部分，让这些犬只六周内只喂食鸡肉水解物日粮。在饮食试验期间排除了体外寄生虫感染和微生物感染。在犬只开始饮食前、恢复原饮食前及恢复后，对其皮肤损伤、胃肠道症状和排便频率进行评估，并对瘙痒程度进行评分。如果犬只在食用该日粮期间瘙痒症状消失，但恢复原饮食时复发，则诊断为食物不良反应。63只犬中有17只退出试验，其中4只因日粮适口性差退出；然而，据报告48只犬对该日粮的适口性评价为良好或极佳。46只犬中有9只（19.6%）被诊断为单纯食物不良反应，另有9只同时存在食物不良反应和特应性。9只出现食物不良反应的犬中有6只出现胃肠道症状，这些症状在试验日粮期间消失，但恢复原饮食时复发。
