Dogan Songuel, Machicao Fausto, Wallwiener Diethelm, Haering Hans-Ulrich, Diedrich Klaus, Hornung Daniela
Fertil Steril. 2004 May;81(5):1411-3. doi: 10.1016/j.fertnstert.2003.10.026.
We explored the association of the PPAR-gamma2 (peroxisome proliferator-activated receptor) Pro-12-Ala polymorphism with endometriosis in a case-control study with 51 women with endometriosis stages I-IV and 55 control women without endometriosis. The 12-Pro allele of PPAR-gamma2 may have protective effects avoiding the development and progression of endometriosis.
我们在一项病例对照研究中，对51名患有I-IV期子宫内膜异位症的女性和55名无子宫内膜异位症的对照女性，探讨了PPAR-γ2（过氧化物酶体增殖物激活受体）Pro-12-Ala多态性与子宫内膜异位症的关联。PPAR-γ2的12-Pro等位基因可能具有避免子宫内膜异位症发生和进展的保护作用。
