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[儿童食物过敏时胰腺功能状态、脂质过氧化及抗氧化防御的特征]

[Characteristics of the functional state of the pancreas, lipid peroxidation and antioxidant defense in food hypersensitivity in children].

作者信息

Dorofeeva G D, Bondar' L S, Lepikhov P A, Prilutskiĭ A S

出版信息

Pediatriia. 1992(3):18-22.

PMID:1513645
Abstract

Pancreas function, lipid peroxidation and antioxidant defence were studied in 154 children aged 1 to 14 years with food allergy. Allergic inflammation due to food allergy favours the origin of different abnormalities of pancreas function: functional (39.4%), reactive pancreatitis (31.3%), chronic pancreatitis (20.1%), and sclerosing chronic pancreatitis (9.2%). They occur in combination with lipid peroxidation activation and a decrease in antioxidant defence. The intensity of the latter ones is dependent on the variety of pancreas function disturbance. The most significant changes in lipid peroxidation and antioxidant defence were discovered in chronic pancreatitis.

摘要

对154名1至14岁的食物过敏儿童的胰腺功能、脂质过氧化和抗氧化防御进行了研究。食物过敏引起的过敏性炎症有利于胰腺功能出现不同异常:功能性异常(39.4%)、反应性胰腺炎(31.3%)、慢性胰腺炎(20.1%)和硬化性慢性胰腺炎(9.2%)。它们与脂质过氧化激活和抗氧化防御能力下降同时出现。后者的强度取决于胰腺功能紊乱的类型。在慢性胰腺炎中发现脂质过氧化和抗氧化防御方面的变化最为显著。

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Pediatriia. 1992(3):18-22.
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