具有类似聚合酶链式反应灵敏度的基于生物条形码的DNA检测。
Bio-bar-code-based DNA detection with PCR-like sensitivity.
作者信息
Nam Jwa-Min, Stoeva Savka I, Mirkin Chad A
机构信息
Department of Chemistry and Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, USA.
出版信息
J Am Chem Soc. 2004 May 19;126(19):5932-3. doi: 10.1021/ja049384+.
PMID:15137735
Abstract
Novel two-component oligonucleotide-modified nanoparticle probes have been designed and used in a bio-bar-code assay with a 500 zeptomolar target DNA sensitivity limit.
摘要
新型双组分寡核苷酸修饰的纳米颗粒探针已被设计出来，并用于生物条形码分析，其对目标DNA的检测灵敏度极限为500仄摩尔。
Zotero 插件