Barnabé W, de Mendonça Neto T, Pimenta F C, Pegoraro L F, Scolaro J M
Department of Prosthodontics, Bauru School of Dentistry, University of São Paulo, São Paulo, Brazil.
J Oral Rehabil. 2004 May;31(5):453-9. doi: 10.1111/j.1365-2842.2004.01254.x.
This study evaluated the reduction of denture stomatitis and the antimicrobial activity of 0.05% sodium hypochlorite opposed to Candida albicans and Streptococcus mutans (SGM) when associated with brushing complete dentures with coconut soap. The mucosal characteristics were evaluated according to Newton's classification at baseline, after cleansing the dentures with coconut soap for 15 days in group 1 (nine patients). In the other group (19 patients) the analysis were made before and after cleansing the dentures with coconut soap and with disinfection in a soak solution of 0.05% sodium hypochlorite for 10 min during 15 days. Microbiological tests were used to isolate C. albicans and SGM. Mann-Whitney and Wilcoxon tests were used to compare the mucosal characteristics and Fisher test and McNemar test to compare C. albicans and SGM levels. Statistical analysis at the 95% confidence level (P < 0.05) showed that: (i) the association of coconut soap and 0.05% sodium hypochlorite significantly reduced clinical signs of denture stomatitis, (ii) C. albicans did not reduce in counts, (iii) SGM were reduced but not significantly and (iv) the association of coconut soap and 0.5% sodium hypochlorite was effective in controlling denture biofilm.
本研究评估了0.05%次氯酸钠与椰子皂一起刷洗全口义齿时,对义齿性口炎的减轻作用以及对白色念珠菌和变形链球菌(SGM)的抗菌活性。在第1组(9名患者)中,用椰子皂清洁义齿15天后,根据牛顿分类法在基线时评估黏膜特征。在另一组(19名患者)中,在15天内,在用椰子皂清洁义齿前后以及在0.05%次氯酸钠浸泡溶液中消毒10分钟后进行分析。采用微生物学检测分离白色念珠菌和SGM。使用曼-惠特尼检验和威尔科克森检验比较黏膜特征,使用费舍尔检验和麦克尼马尔检验比较白色念珠菌和SGM水平。在95%置信水平(P < 0.05)下的统计分析表明:(i)椰子皂和0.05%次氯酸钠联合使用可显著减轻义齿性口炎的临床症状,(ii)白色念珠菌数量未减少,(iii)SGM数量减少但不显著,(iv)椰子皂和0.5%次氯酸钠联合使用对控制义齿生物膜有效。