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急性心肌梗死患者急诊冠状动脉血管成形术护理质量指标的可比性,无论现场是否有心脏手术(来自国家心肌梗死登记处的报告)

Comparability of quality-of-care indicators for emergency coronary angioplasty in patients with acute myocardial infarction regardless of on-site cardiac surgery (report from the National Registry of Myocardial Infarction).

作者信息

Sanborn Timothy A, Jacobs Alice K, Frederick Paul D, Every Nathan R, French William J

机构信息

Feinberg School of Medicine, Northwestern University, Evanston Northwestern Healthcare, Burch 300, 2650 Ridge Avenue, Evanston, IL 60201, USA.

出版信息

Am J Cardiol. 2004 Jun 1;93(11):1335-9, A5. doi: 10.1016/j.amjcard.2004.02.026.

Abstract

Initial reports have suggested that primary percutaneous coronary intervention (PCI) can be performed safely in selected hospitals without on-site cardiac surgery; however, quality-of-care indicators for primary PCI in these institutions is unknown. Therefore, symptom onset-to-door intervals, door-to-balloon times, compliance with American College of Cardiology/American Heart Association (ACC/AHA) management guidelines, and in-hospital mortality were evaluated in 108,132 patients in 3 hospital settings in the National Registry of Myocardial Infarction: (1) diagnostic laboratories only (n = 47), (2) elective PCI only (n = 50), and (3) elective PCI and cardiac surgery (n = 562). Mean symptom onset-to-door intervals (127 minutes, 95% confidence interval 118 to135; 134 minutes, 95% confidence interval 125 to 142; and 140 minutes, 95% confidence intervals 138 to 141; p = 0.01) and door-to-balloon intervals (104 minutes, 95% confidence interval 101 to 108; 116 minutes, 95% confidence interval 112 to 119; and 119 minutes, 95% confidence interval 118 to 120; p <0.0001) were shorter in hospitals without cardiac surgery. Adherence to ACC/AHA guidelines for medications within the first 24 hours (aspirin, beta blockers, angiotensin-converting enzyme inhibitors) was greater in hospitals without cardiac surgery. There were comparable in-hospital mortality rates (3.2%, 4.2%, and 4.8%, respectively; p = 0.07) for patients with similar Thrombolysis In Myocardial Infarction risk scores; however, 4.7% of patients treated with primary PCI in hospitals without cardiac surgery were transferred to another institution. Thus, hospitals performing primary PCI without on-site cardiac surgery that participated in this registry have quality-of-care indicators and adherence to ACC/AHA management guidelines that are comparable to hospitals with on-site cardiac surgery. The lack of on-site cardiac surgery does not appear to adversely affect quality-of-care indicators in primary PCI.

摘要

初步报告显示,在一些没有现场心脏手术条件的特定医院中,也能够安全地进行直接经皮冠状动脉介入治疗(PCI);然而,这些机构中直接PCI的医疗质量指标尚不清楚。因此,在国家心肌梗死注册中心的3种医院环境中,对108,132例患者的症状发作至入院时间、入院至球囊扩张时间、美国心脏病学会/美国心脏协会(ACC/AHA)管理指南的依从性以及院内死亡率进行了评估:(1)仅设有诊断实验室的医院(n = 47),(2)仅开展择期PCI的医院(n = 50),以及(3)开展择期PCI和心脏手术的医院(n = 562)。在没有心脏手术的医院中,平均症状发作至入院时间(127分钟,95%置信区间118至135;134分钟,95%置信区间125至142;以及140分钟,95%置信区间138至141;p = 0.01)和入院至球囊扩张时间(104分钟,95%置信区间101至108;116分钟,95%置信区间112至119;以及119分钟,95%置信区间118至120;p <0.0001)更短。在没有心脏手术的医院中,患者在最初24小时内对ACC/AHA药物治疗指南(阿司匹林、β受体阻滞剂、血管紧张素转换酶抑制剂)的依从性更高。对于具有相似心肌梗死溶栓风险评分的患者,院内死亡率相当(分别为3.2%、4.2%和4.8%;p = 0.07);然而,在没有心脏手术的医院中接受直接PCI治疗的患者中有4.7%被转至另一机构。因此,参与本注册研究的、没有现场心脏手术条件而开展直接PCI的医院,其医疗质量指标以及对ACC/AHA管理指南的依从性与设有现场心脏手术的医院相当。缺乏现场心脏手术似乎并未对直接PCI的医疗质量指标产生不利影响。

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