Mikami Toshiyuki, Nakagomi Toyoko, Tsutsui Rika, Ishikawa Kazuko, Onodera Yohko, Arisawa Kokichi, Nakagomi Osamu
Department of Microbiology, Aomori Prefectural Institute of Public Health and Environment, Aomori, Japan.
J Med Virol. 2004 Jul;73(3):460-4. doi: 10.1002/jmv.20112.
Between May14 and 18, 2001, there was an outbreak of acute gastroenteritis involving 45 school children out of a total of 107 (aged 11-12 years) attending a 3-day school trip. The epidemic curve characterized by a rapid onset and decline with a single peak incidence over a 5-day period resembled the pattern typical of a food-borne gastroenteritis outbreak. Epidemiological and virological investigations concluded, however, that this outbreak was caused by a single strain of serotype G2 group A rotavirus spreading to schoolmates from the primary case-pupil who had already been ill at the start of the trip. Efficient person-to-person transmission was likely to have occurred due to prolonged and close contacts under the conditions typical of such school trips. This study emphasizes the importance of including group A rotavirus infection as a possible cause of gastroenteritis outbreaks even in older children and adults.
2001年5月14日至18日期间，107名（年龄在11至12岁）参加为期3天学校旅行的学生中有45名爆发了急性肠胃炎。疫情曲线的特点是发病迅速且消退迅速，在5天内出现单一发病高峰，类似食源性肠胃炎爆发的典型模式。然而，流行病学和病毒学调查得出结论，此次疫情是由一株G2血清型A组轮状病毒引起的，该病毒从旅行开始时就已患病的首例学生传播给了其他同学。由于在这类学校旅行的典型条件下长时间密切接触，很可能发生了有效的人际传播。本研究强调，即使在大龄儿童和成人中，也应将A组轮状病毒感染作为肠胃炎爆发的可能原因之一。
