Globe Denise R, Wu Joanne, Azen Stanley P, Varma Rohit
Department of Pharmaceutical Economics and Policy, School of Pharmacy, University of Southern California, Los Angeles, California, USA.
Ophthalmology. 2004 Jun;111(6):1141-9. doi: 10.1016/j.ophtha.2004.02.003.
To assess the association between presenting binocular visual acuity (VA) and self-reported visual function as measured by the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25).
A population-based, prevalence study of eye disease in Latinos 40 years and older residing in La Puente, California (Los Angeles Latino Eye Study [LALES]).
Six thousand three hundred fifty-seven Latinos 40 years and older from 6 census tracts in La Puente.
All participants completed a standardized interview, including the NEI-VFQ-25 to measure visual functioning, and a detailed eye examination. Two definitions of visual impairment were used: (1) presenting binocular distance VA of 20/40 or worse and (2) presenting binocular distance VA worse than 20/40. Analysis of variance was used to determine any systematic differences in mean NEI-VFQ-25 scores by visual impairment. Regression analyses were completed (1) to determine the association of age, gender, number of systemic comorbidities, depression, and VA with self-reported visual function and (2) to estimate a visual impairment-related difference for each subscale based on differences in VA.
The NEI-VFQ-25 scores in persons with visual impairment.
Of the 5287 LALES participants with complete NEI-VFQ-25 data, 6.3% (including 20/40) and 4.2% (excluding 20/40) were visually impaired. In the visually impaired participants, the NEI-VFQ-25 subscale scores ranged from 46.2 (General Health) to 93.8 (Color Vision). In the regression model, only VA, depression, and number of comorbidities were significantly associated with all subscale scores (R(2) ranged from 0.09 for Ocular Pain to 0.33 for the composite score). For 9 of 11 subscales, a 5-point change was equivalent to a 1- or 2-line difference in VA. Relationships were similar regardless of the definition of visual impairment.
In this population-based study of Latinos, the NEI-VFQ-25 was sensitive to differences in VA. A 5-point difference on the NEI-VFQ-25 seems to be a minimal criterion for a visual impairment-related difference. Self-reported visual function is essentially unchanged if the definition of visual impairment includes or excludes a VA of 20/40.
通过25项美国国立眼科研究所视觉功能问卷(NEI-VFQ-25)评估双眼初始视力(VA)与自我报告的视觉功能之间的关联。
对居住在加利福尼亚州拉蓬特市(洛杉矶拉丁裔眼病研究[LALES])的40岁及以上拉丁裔人群进行基于人群的眼病患病率研究。
来自拉蓬特市6个人口普查区的6357名40岁及以上的拉丁裔。
所有参与者均完成了标准化访谈,包括用于测量视觉功能的NEI-VFQ-25,以及详细的眼科检查。采用了两种视力损害的定义:(1)双眼初始远距离视力为20/40或更差;(2)双眼初始远距离视力低于20/40。采用方差分析来确定按视力损害分类的NEI-VFQ-25平均得分的任何系统差异。完成回归分析:(1)确定年龄、性别、全身合并症数量、抑郁和视力与自我报告的视觉功能之间的关联;(2)根据视力差异估计每个子量表与视力损害相关的差异。
视力损害者的NEI-VFQ-25得分。
在5287名有完整NEI-VFQ-25数据的LALES参与者中,6.3%(包括20/40)和4.2%(不包括20/40)存在视力损害。在视力损害的参与者中,NEI-VFQ-25子量表得分范围为46.2(总体健康)至93.8(色觉)。在回归模型中,只有视力、抑郁和合并症数量与所有子量表得分显著相关(R²范围从眼痛的0.09到综合得分的0.33)。对于11个子量表中的9个,5分的变化相当于视力1行或2行的差异。无论视力损害的定义如何,关系相似。
在这项基于人群的拉丁裔研究中,NEI-VFQ-25对视力差异敏感。NEI-VFQ-25上5分的差异似乎是与视力损害相关差异的最小标准。如果视力损害的定义包括或排除20/40的视力,则自我报告的视觉功能基本不变。