From the Department of Preventive Medicine and the Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Southern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, California, USA.
Am J Ophthalmol. 2021 Sep;229:52-62. doi: 10.1016/j.ajo.2021.02.008. Epub 2021 Feb 8.
To elucidate how visual field loss (VFL) impacts self-reported vision-specific quality of life (VSQOL) in African Americans, who experience a disproportionate burden of visual impairment.
Cross-sectional, population-based cohort.
Eligible participants (n = 7,957) were recruited who self-identified as African American, were aged 40 years or older, and resided in Inglewood, California, USA. A total of 6,347 participants (80.0%) completed clinical eye examinations. Total mean deviation (MD) of VFL was measured bilaterally as decibels (dB) using the Humphrey SITA Standard 24-2 test. VSQOL was measured using the National Eye Institute Visual Function Questionnaire (NEI-VFQ 25) and scored using item response theory (IRT).
Participants with reliable data (n = 5,121) had a mean age of 60.7 years (standard deviation 11.0); those with worse VFL were older; had more comorbidities, lower income, less education, and worse visual acuity; and were more likely to be unemployed and depressed. Using IRT analysis, a change in VF of 6.2 (95% confidence interval [CI]: 5.3, 7.7) dB and 9.2 (95% CI: 7.5, 11.9) dB was necessary to observe a meaningful (5-point) difference in vision-related task and emotional well-being scores, respectively. VFL had the greatest impact on self-reported driving ability (6.0 dB [95% CI: 5.2, 7.1]), followed by satisfaction with general vision, near vision, vision-related mental health, and peripheral vision.
The strongest impact of VFL reported by African Americans was on their ability to complete visual tasks, especially for driving. An effect of VFL on emotional well-being also was observed, but the magnitude of association was about 50% lower for well-being compared to that of task.
阐明视野丧失(VFL)如何影响美国非裔人群的视觉特异性生活质量(VSQOL)自评,因为非裔人群的视力障碍负担不成比例。
横断面、基于人群的队列研究。
招募了符合条件的参与者(n=7957),他们自我认定为非裔,年龄在 40 岁或以上,居住在美国加利福尼亚州英格尔伍德。共有 6347 名参与者(80.0%)完成了临床眼部检查。使用 Humphrey SITA Standard 24-2 测试,双侧以分贝(dB)测量 VFL 的总平均偏差(MD)。使用国家眼科研究所视觉功能问卷(NEI-VFQ 25)测量 VSQOL,并使用项目反应理论(IRT)进行评分。
具有可靠数据的参与者(n=5121)的平均年龄为 60.7 岁(标准差为 11.0);视野较差者年龄较大;患有更多的合并症,收入较低,受教育程度较低,视力更差;且更有可能失业和抑郁。使用 IRT 分析,VF 变化 6.2(95%置信区间[CI]:5.3,7.7)dB 和 9.2(95% CI:7.5,11.9)dB 分别观察到与视觉相关任务和情感健康评分相关的有意义(5 分)差异。VFL 对自我报告的驾驶能力影响最大(6.0 dB [95% CI:5.2,7.1]),其次是对总体视力、近视力、与视力相关的心理健康和周边视力的满意度。
美国非裔人群报告的 VFL 影响最大的是他们完成视觉任务的能力,尤其是驾驶能力。还观察到 VFL 对情感健康的影响,但与任务相比,健康的关联程度低约 50%。