Botelho Michael G
Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong, China, SAR.
SADJ. 2004 Mar;59(2):51-3.
Glass ionomer cements have been suggested for obturating carious teeth that have been prepared with dental hand instruments. In such cases, carious dentine may be inadvertently or deliberately left in situ. The residual bacteria may, over time, lead to secondary caries and restoration failure. Benefit may be gained from combining antibacterial agents with the glass ionomer cement to control residual bacteria. The aim of this study was to investigate the effects on the compressive strength of glass ionomer cement combined with oral antibacterial agents. Cationic antibacterial agents; chlorhexidine hydrochloride, cetylpyridinium chloride and cetrimide were added to the powder and benzalkonium chloride, a liquid, to the liquid of Fuji IX glass ionomer cement. These were prepared to concentrations of 1, 2 and 4 per cent by weight of the glass ionomer cement and compared to Fuji IX with no antibacterial agent. Test specimens were subjected to a compressive force to failure. Multiple analysis of variance showed highly significant reductions in compressive strength (p < 0.01) between the test materials and control group apart from one per cent benzalkonium chloride. Increasing concentration of the antibacterial agent had increasing adverse effects on the physical properties. The addition of the antibacterial agents tested to Fuji IX reduces the seven-day compressive strength which may affect the clinical performance of the material.
玻璃离子水门汀已被建议用于充填用牙科手动器械制备的龋洞型牙齿。在这种情况下，龋坏牙本质可能会被无意或有意地留在原位。随着时间的推移，残留细菌可能会导致继发龋和修复失败。将抗菌剂与玻璃离子水门汀结合以控制残留细菌可能会有好处。本研究的目的是调查口腔抗菌剂与玻璃离子水门汀结合对其抗压强度的影响。将阳离子抗菌剂；盐酸氯己定、西吡氯铵和溴棕三甲基铵添加到粉剂中，将苯扎氯铵（一种液体）添加到富士IX玻璃离子水门汀的液剂中。这些抗菌剂按玻璃离子水门汀重量的1%、2%和4%进行配制，并与不含抗菌剂的富士IX进行比较。对测试标本施加压缩力直至破坏。多因素方差分析显示，除1%的苯扎氯铵外，测试材料与对照组之间的抗压强度有极显著降低（p<0.01）。抗菌剂浓度的增加对物理性能有越来越大的不利影响。向富士IX中添加测试的抗菌剂会降低其7天抗压强度，这可能会影响该材料的临床性能。
