Dimkov A, Nicholson W J, Gjorgievska E, Booth S
Clinic for Paediatric and Preventive Dentistry, Faculty of Dentistry, Skopje, R. Macedonia.
Prilozi. 2012;33(1):243-63.
Because of the relatively frequent occurrence of recurrent caries after a restorative treatment, and because of the huge number of cariogenic microorganisms present in the oral cavity, which present a potential risk factor regarding the development of new carious lesions, attention has increasingly been directed towards the therapeutic antimicrobial effects of restorative materials. The glass ionomer cements distinguish themselves as the most acceptable restorative materials possessing the positive characteristics of fluorine in the processes of remineralisation and antimicrobial action. In addition to the release of fluoride ions, GICs can potentially be used as templates for the release of other active antimicrobial components. The addition of antimicrobial compounds in the glass ionomer cements and analysis of their physical characteristics are very important especially for use in the posterior region of milk teeth. The aim of this study was to analyse the physical characteristics of ChemFlex and Fuji IX, conventional glass ionomer cements incorporated with the antimicrobial components Cetylpyridinium Chloride and Benzalkonium Chloride, through measurements of their setting times, and determination of their compressive strengths. Five samples of each glass ionomer with no antimicrobial compounds added were prepared--to serve as a control group; and collections of five samples of each cement with different concentrations of Cetylpyridinium Chloride and Benzalkonium Chloride--1%, 2% and 3%--added to them were also prepared--a total of 60 samples. The results of the analysis point out that it is possible to incorporate these antimicrobial agents in conventional GICs, and this is especially true when the added amount of the antimicrobial agents is 1%.
由于修复治疗后龋齿复发相对频繁，且口腔中存在大量致龋微生物，这是新龋损形成的潜在危险因素，因此人们越来越关注修复材料的治疗性抗菌作用。玻璃离子水门汀作为最可接受的修复材料脱颖而出，在再矿化和抗菌作用过程中具有氟的积极特性。除了释放氟离子外，玻璃离子水门汀还可潜在地用作其他活性抗菌成分释放的模板。在玻璃离子水门汀中添加抗菌化合物并分析其物理特性非常重要，尤其是用于乳牙后部区域时。本研究的目的是通过测量其凝固时间和测定其抗压强度，分析掺入抗菌成分十六烷基氯化吡啶和苯扎氯铵的传统玻璃离子水门汀ChemFlex和Fuji IX的物理特性。制备了五个未添加抗菌化合物的每种玻璃离子水门汀样品作为对照组；还制备了添加了不同浓度（1%、2%和3%）十六烷基氯化吡啶和苯扎氯铵的每种水门汀的五个样品，共60个样品。分析结果表明，在传统玻璃离子水门汀中掺入这些抗菌剂是可能的，当抗菌剂添加量为1%时尤其如此。
