Tucker S M, Bhattacharya J
Hillingdon Hospital Postgraduate Centre, Uxbridge, Middlesex.
Arch Dis Child. 1992 Jul;67(7):911-9. doi: 10.1136/adc.67.7.911.
The Auditory Response Cradle (ARC) is a fully automated microprocessor controlled machine that was designed for the hearing screening of full term neonates. In order to evaluate the ARC, 6000 babies were screened at a district maternity hospital over a period of three years. Every infant subsequently entered a three year follow up programme. One hundred and two babies (1.7%) failed the ARC screen (that is, they failed two ARC tests) and 20 of these were found to have some hearing impairment: in 10 it was severe (80-90 dBHL), in seven moderate (45-60 dBHL), and in three it was mild to moderate (less than 45 dBHL). In addition, of the 20 babies who failed a first test and were discharged before a second could be performed, two were confirmed to have a severe hearing loss; 79 infants failing the screen were cleared on further testing, giving the ARC a false positive rate of 1.3%. On following up all 6000 infants for three years, seven children who passed the neonatal screen were subsequently found to have a hearing loss. For two babies the aetiology was unknown but for five the hearing impairment was either due to a hereditary progressive loss or definite postnatal factors. Progressive and acquired hearing losses cannot be detected at a neonatal screen and this emphasises the need for follow up screens at other stages in the child's life. In this long term study the ARC has been found to have a high detection rate for severe hearing loss and confirms the practical possibility of using a behavioural technique for the universal screening of hearing in neonates.
听觉反应摇篮(ARC)是一台完全自动化的、由微处理器控制的机器,专为足月儿听力筛查而设计。为了评估ARC,在一家地区妇产医院对6000名婴儿进行了为期三年的筛查。随后,每个婴儿都进入了一个为期三年的随访项目。102名婴儿(1.7%)未通过ARC筛查(即他们未能通过两次ARC测试),其中20名被发现有某种听力障碍:10名是重度(80 - 90 dBHL),7名是中度(45 - 60 dBHL),3名是轻度至中度(低于45 dBHL)。此外,在20名首次测试未通过且在进行第二次测试前已出院的婴儿中,有2名被确诊为重度听力损失;79名筛查未通过的婴儿在进一步测试后被排除,ARC的假阳性率为1.3%。在对所有6000名婴儿进行三年随访后,发现7名通过新生儿筛查的儿童随后出现了听力损失。对于2名婴儿,病因不明,但对于5名婴儿,听力障碍要么是由于遗传性进行性听力损失,要么是明确的出生后因素。进行性和后天性听力损失在新生儿筛查中无法检测到,这强调了在儿童生命的其他阶段进行后续筛查的必要性。在这项长期研究中,ARC被发现对重度听力损失具有较高的检测率,并证实了使用行为技术对新生儿进行普遍听力筛查的实际可行性。