Gustafsson D, Löwhagen T, Andersson K
Department of Paediatrics, Orebro Medical Centre Hospital, Sweden.
Arch Dis Child. 1992 Aug;67(8):1008-10. doi: 10.1136/adc.67.8.1008.
A follow up of a cohort of 736 healthy full term children with exposure to cows' milk based formula and breast milk from donors on the maternity ward was performed. The children were divided into three exposure groups according to the feeding patterns on the maternity ward. Group 1 received only mother's milk, group 2 mother's milk and human donors' milk, and group 3 received mother's milk, donors' milk and cows' milk based formula. The children were investigated at 7 years of age, by examining their medical files, and at 11 and 14 years, by questionnaires regarding symptoms of atopic disease. No significant differences between the three groups at follow up were found in the cumulative incidences of atopic diseases. The amount of formula given did not affect the risk of developing atopic disease. Children with a family history of such diseases ran the same risk of subsequent atopic disease whether they were fed formula or breast milk alone. Cows' milk based formula given on the maternity ward does not seem to increase the risk of developing atopic disease.
对一组736名足月健康儿童进行了随访,这些儿童在产科病房接触了基于牛乳的配方奶粉和来自捐赠者的母乳。根据产科病房的喂养模式,将儿童分为三个接触组。第1组仅接受母乳,第2组接受母乳和人类捐赠者的母乳,第3组接受母乳、捐赠者的母乳和基于牛乳的配方奶粉。在儿童7岁时通过查阅他们的病历进行调查,在11岁和14岁时通过关于特应性疾病症状的问卷进行调查。在随访中,三组之间特应性疾病的累积发病率没有显著差异。给予的配方奶粉量不影响患特应性疾病的风险。有此类疾病家族史的儿童,无论单独喂食配方奶粉还是母乳,患后续特应性疾病的风险相同。产科病房给予的基于牛乳的配方奶粉似乎不会增加患特应性疾病的风险。