Weinrach Jonathan C, Cronin Ernest D, Smith Bruce K, Collins Donald R, Cohen Benjamin E
CHRISTUS St. Joseph Hospital, Plastic Surgery Residency Program, Houston, TX 77002, USA.
Ann Plast Surg. 2004 Jul;53(1):12-6. doi: 10.1097/01.sap.0000112286.30212.12.
Donor site seroma continues to be the most common complication of latissimus dorsi flap reconstruction. Numerous preventive methods and treatments have been described. The use of fibrin sealant in the donor site before closure may be an effective means of seroma prevention. The authors evaluated the efficacy of fibrin sealant in conjunction with closed suction drainage in a series of 17 latissimus flap donor sites. They also determined their approximate institutional seroma rate with a retrospective chart review of 20 donor sites. The fibrin sealant patients had a seroma rate of 11.8% compared with a rate of 35% among the untreated patients (P = 0.047). This compares favorably with seroma rates as high as 79% described in the literature. In conclusion, the use of fibrin sealant in the latissimus flap donor site appears to be effective in preventing seroma.
供区血清肿仍然是背阔肌肌皮瓣重建最常见的并发症。已有多种预防方法和治疗手段被描述。在关闭切口前于供区使用纤维蛋白封闭剂可能是预防血清肿的一种有效方法。作者在17例背阔肌肌皮瓣供区评估了纤维蛋白封闭剂联合闭式负压引流的疗效。他们还通过对20个供区进行回顾性图表分析确定了本机构大致的血清肿发生率。使用纤维蛋白封闭剂的患者血清肿发生率为11.8%，而未治疗患者的发生率为35%（P = 0.047）。这与文献中高达79%的血清肿发生率相比具有优势。总之，在背阔肌肌皮瓣供区使用纤维蛋白封闭剂似乎对预防血清肿有效。
