Eichler Christian, Dahdouh Faten, Sauerwald Axel, Warm Mathias
Department of Gynecology and Obstetrics, Holweide Hospital, Cologne, Germany.
J Med Case Rep. 2013 May 28;7:138. doi: 10.1186/1752-1947-7-138.
Post-mastectomy seromas are a common problem in modern oncological surgery. Occurrence rates of up to 59% have been reported in the literature. High-risk patients, that is, those who have received previous surgeries, radiation or chemotherapy, present a particular challenge. Several surgical techniques, including progressive tension suture application, have shown promise. Noninvasive measures such as fibrin-based adhesives have thus far not been able to prevent seroma occurrence effectively. A recent study using a lysine-derived urethane adhesive named TissuGlu®, however, showed promising results in patients after abdominoplasty.
We used TissuGlu® to treat a high-risk 64-year-old female patient with a history of breast cancer and severe post-mastectomy seroma. The postsurgical period showed successful seroma suppression, without any adverse effects or complications.
This type of adhesive should be evaluated as an alternative, less-invasive option for preventing seroma in patients after a mastectomy.
乳房切除术后血清肿是现代肿瘤外科手术中常见的问题。文献报道发生率高达59%。高危患者，即那些曾接受过手术、放疗或化疗的患者，面临着特殊的挑战。包括应用渐进性张力缝合在内的几种手术技术已显示出前景。迄今为止，诸如基于纤维蛋白的粘合剂等非侵入性措施尚无法有效预防血清肿的发生。然而，最近一项使用名为TissuGlu®的赖氨酸衍生聚氨酯粘合剂的研究，在腹部整形术后患者中显示出了有前景的结果。
我们使用TissuGlu®治疗了一名64岁的高危女性患者，她有乳腺癌病史且乳房切除术后血清肿严重。术后血清肿得到成功抑制，未出现任何不良反应或并发症。
这种粘合剂应作为一种预防乳房切除术后患者血清肿的侵入性较小的替代选择进行评估。
