重新评估脑弹性以分析脑积水的生物力学机制。
Reassessment of brain elasticity for analysis of biomechanisms of hydrocephalus.
作者信息
Taylor Zeike, Miller Karol
机构信息
School of Mechanical and Materials Engineering, The University of Western Australia, 35 Stirling Highway, Crawley/Perth, WA 6009, Australia.
出版信息
J Biomech. 2004 Aug;37(8):1263-9. doi: 10.1016/j.jbiomech.2003.11.027.
This paper presents results from a finite element study of the biomechanics of hydrocephalus, with special emphasis on a reassessment of the parenchyma elastic modulus. A two-dimensional finite element model of the human brain/ventricular system is developed and analysed under hydrocephalic loading conditions. It is shown that the Young's modulus of the brain parenchyma used in previous studies (3000-10000 Pa) corresponds to strain rates much higher than those present in hydrocephalic brains. Consideration of the brain's viscoelasticity leads to the derivation of a considerably lower modulus value of approximately 584 Pa.
本文介绍了一项关于脑积水生物力学的有限元研究结果，特别强调了对脑实质弹性模量的重新评估。建立了一个人脑/脑室系统的二维有限元模型，并在脑积水负荷条件下进行了分析。结果表明，先前研究中使用的脑实质杨氏模量（3000 - 10000帕斯卡）对应的应变率远高于脑积水患者大脑中的应变率。考虑到大脑的粘弹性，得出了一个低得多的模量值，约为584帕斯卡。
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