生物信息3D：一套用于结构生物信息学的工具。
BioInfo3D: a suite of tools for structural bioinformatics.
作者信息
Shatsky Maxim, Dror Oranit, Schneidman-Duhovny Dina, Nussinov Ruth, Wolfson Haim J
机构信息
School of Computer Science, Raymond and Beverly Sackler Faculty of Exact Sciences,Tel Aviv University, Tel Aviv 69978, Israel.
出版信息
Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W503-7. doi: 10.1093/nar/gkh413.
Abstract
Here, we describe BioInfo3D, a suite of freely available web services for protein structural analysis. The FlexProt method performs flexible structural alignment of protein molecules. FlexProt simultaneously detects the hinge regions and aligns the rigid subparts of the molecules. It does not require an a priori knowledge of the flexible hinge regions. MultiProt and MASS perform simultaneous comparison of multiple protein structures. PatchDock performs prediction of protein-protein and protein-small molecule interactions. The input to all services is either protein PDB codes or protein structures uploaded to the server. All the services are available at http://bioinfo3d.cs.tau.ac.il.
摘要
在此，我们介绍BioInfo3D，这是一套免费提供的用于蛋白质结构分析的网络服务。FlexProt方法可对蛋白质分子进行灵活的结构比对。FlexProt能同时检测铰链区并比对分子的刚性子部分。它不需要预先了解灵活的铰链区。MultiProt和MASS可对多个蛋白质结构进行同步比较。PatchDock可预测蛋白质-蛋白质和蛋白质-小分子相互作用。所有服务的输入可以是蛋白质PDB代码或上传到服务器的蛋白质结构。所有服务均可在http://bioinfo3d.cs.tau.ac.il获取。
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