Van den Broek W T, Makay O, Berends F J, Yuan J Z, Houdijk A P J, Meijer S, Cuesta M A
Department of Surgery, VU Medisch Centrum, Postbus 7057, Amsterdam, The Netherlands.
Surg Endosc. 2004 May;18(5):812-7. doi: 10.1007/s00464-003-9173-y. Epub 2004 Apr 6.
Resection of the esophagus remains the only curative therapy for esophageal cancer. Conventional resections are right-side thoracotomy in combination with laparotomy, gastric tube creation, and the transhiatal approach according to Orringer. This study evaluated laparoscopically assisted transhiatal esophagus resection, which offers perfect visualization of the esophagus during mediastinal dissection without the necessity of a thoracotomy.
In this study, 25 laparoscopically assisted transhiatal esophagus resections were compared with a historical control group consisting of 20 open transhiatal esophagus resections.
Nine laparoscopically assisted resections (36%) were converted to open procedures. The operating time was longer in the laparoscopically assisted group (300 vs 257 min; p < 0.05), but laparoscopically assisted esophagus resection was associated with less blood loss (600 vs 900 ml; p < 0.05) and shorter intensive care unit stay (1 vs 2 days; p < 0.05). There were no differences in morbidity, mortality, and hospital stay. During a shorter follow-up time for the laparoscopic group (17 vs 54 months), 11 patients (44%) in the laparoscopically assisted group and 10 (50%) patients in the open group had recurrence of the disease.
Laparoscopically assisted transhiatal esophagus resection is a safe procedure with important advantages, as compared with the open procedure, such as less blood loss and shorter intensive care unit stay. At this point, the oncologic consequences are not clear.
食管切除术仍然是食管癌唯一的根治性治疗方法。传统的切除术是右侧开胸联合剖腹术、胃管制作以及根据奥林格方法进行的经裂孔途径。本研究评估了腹腔镜辅助经裂孔食管切除术,该方法在纵隔解剖过程中能提供食管的完美视野,且无需开胸。
在本研究中,将25例腹腔镜辅助经裂孔食管切除术与由20例开放经裂孔食管切除术组成的历史对照组进行比较。
9例腹腔镜辅助切除术(36%)转为开放手术。腹腔镜辅助组的手术时间更长(300分钟对257分钟;p<0.05),但腹腔镜辅助食管切除术的失血量更少(600毫升对900毫升;p<0.05),重症监护病房住院时间更短(1天对2天;p<0.05)。在发病率、死亡率和住院时间方面没有差异。在腹腔镜组较短的随访时间(17个月对54个月)内,腹腔镜辅助组有11例患者(44%)疾病复发,开放组有10例患者(50%)疾病复发。
与开放手术相比,腹腔镜辅助经裂孔食管切除术是一种安全的手术方法,具有重要优势,如失血量更少和重症监护病房住院时间更短。目前,肿瘤学方面的后果尚不清楚。