Athanasas Konstantinos, Magiatis Prokopios, Fokialakis Nikolas, Skaltsounis Alexios-Leandros, Pratsinis Harris, Kletsas Dimitris
Laboratory of Pharmacognosy and Natural Products Chemistry, Department of Pharmacy, University of Athens, Panepistimiopolis Zografou, GR-15771 Athens, Greece.
J Nat Prod. 2004 Jun;67(6):973-7. doi: 10.1021/np034051w.
Two new and four known phloroglucinol derivatives were isolated from the dichloromethane extract of the Greek endemic plant Hypericum jovis. Their antioxidant activity was evaluated in vitro with the DPPH assay and in cell cultures using the DCFH-DA assay. All six compounds demonstrated significant antioxidant activity, while two of them possessed activity at a cellular level comparable to Trolox, protecting against ROS.
从希腊特有植物朱庇特金丝桃的二氯甲烷提取物中分离出两种新的和四种已知的间苯三酚衍生物。采用DPPH法在体外对其抗氧化活性进行了评估，并使用DCFH-DA法在细胞培养物中进行了评估。所有六种化合物均表现出显著的抗氧化活性，其中两种在细胞水平上的活性与Trolox相当，可抵御活性氧。
