School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Road, Section 1, Taipei 100, Taiwan.
Nat Prod Res. 2013 Apr;27(8):727-34. doi: 10.1080/14786419.2012.695365. Epub 2012 Jun 12.
Phytochemical investigation of Hypericum nakamurai (Masamune) Robson has led to the isolation of three phloroglucinol derivatives 1-3. The structures of these compounds were determined by the analysis of their spectroscopic data (IR, mass and UV), and by the application of 1-D and 2-D-NMR techniques. Hyperinakin (1) is a new compound. The anti-inflammatory activities of compounds 1-3 were also tested and evaluated. A biogenetic pathway for compounds 1-3 was also proposed.
对藤黄科金丝桃属植物(麻叶金丝桃)的化学成分研究导致了三个间苯三酚衍生物 1-3 的分离。这些化合物的结构通过分析其光谱数据(IR、质量和 UV)以及应用 1D 和 2D-NMR 技术来确定。Hyperinakin(1)是一种新化合物。还测试和评估了化合物 1-3 的抗炎活性。还提出了化合物 1-3 的生物合成途径。