来自白杆沙拐枣的新芪衍生物。

New stilbene derivatives from Calligonum leucocladum.

作者信息

Okasaka Mamoru, Takaishi Yoshihisa, Kogure Kentarou, Fukuzawa Kenji, Shibata Hirohumi, Higuti Tomihiko, Honda Gisho, Ito Michiho, Kodzhimatov Olimjon K, Ashurmetov Ozodbek

机构信息

Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima, 770-8505, Japan.

出版信息

J Nat Prod. 2004 Jun;67(6):1044-6. doi: 10.1021/np0304823.

DOI:10.1021/np0304823

PMID:15217293

Abstract

Two new stilbene derivatives, (E)-resveratrol 3-(6' '-galloyl)-O-beta-D-glucopyranoside (1) and (E)-resveratrol 3-(4' '-acetyl)-O-beta-D-xylopyranoside (2), and five known stilbene derivatives (3-7) were isolated from the dried aerial parts of Calligonum leucocladum. Their structures were established on the basis of spectroscopic evidence. Compound 1 showed antioxidant activity and a restorative effect of the inhibition of oxacillin to oxacillin/methicillin-resistant Staphylococcus aureus.

摘要

从白枝沙拐枣干燥地上部分分离得到两个新的芪衍生物，（E）-白藜芦醇3-（6''-没食子酰基）-O-β-D-吡喃葡萄糖苷（1）和（E）-白藜芦醇3-（4''-乙酰基）-O-β-D-吡喃木糖苷（2），以及五个已知的芪衍生物（3 - 7）。它们的结构通过光谱证据得以确定。化合物1表现出抗氧化活性以及对苯唑西林抑制苯唑西林/耐甲氧西林金黄色葡萄球菌的恢复作用。