Zhang Chao-Feng, Chen Jing, Zhao Li-Qing, Zhang Dan, Zhang Mian, Wang Zheng-Tao
Key Laboratory of Modern Chinese Medicines, Ministry of Education, Research Department of Pharmacognosy, China Pharmaceutical University, Nanjing, China.
J Asian Nat Prod Res. 2011 Feb;13(2):136-42. doi: 10.1080/10286020.2010.546357.
Five solvent extracts (ethanol, petroleum ether, EtOAC, n-butanol, and water) from Fallopia convolvulus (L.) Love were separated and their inhibitory effects on nitric oxide production in lipopolysaccharide-activated macrophages were evaluated. Three new flavonoids, falloconvolin A (1), falloconvolin B (2), and quercetin-3-O-(2-E-sinapoxyl)-glucopyranoside (3), together with 17 known phenolic compounds, were isolated from the active EtOAC extract, and their structures were elucidated on the basis of spectroscopic analysis and literature data.
对何首乌（Fallopia convolvulus (L.) Love）的五种溶剂提取物（乙醇、石油醚、乙酸乙酯、正丁醇和水）进行了分离，并评估了它们对脂多糖激活的巨噬细胞中一氧化氮产生的抑制作用。从活性乙酸乙酯提取物中分离出三种新的黄酮类化合物，即何首乌苷A（1）、何首乌苷B（2）和槲皮素-3-O-(2-E-芥子酰基)-吡喃葡萄糖苷（3），以及17种已知的酚类化合物，并根据光谱分析和文献数据阐明了它们的结构。
