Krousel-Wood Marie, Thomas Sheila, Muntner Paul, Morisky Donald
Ochsner Clinic Foundation, New Orleans, Louisiana, USA.
Curr Opin Cardiol. 2004 Jul;19(4):357-62. doi: 10.1097/01.hco.0000126978.03828.9e.
Patients' adherence to antihypertensive drug regimens is a complex but important factor in achieving blood pressure control and reducing adverse cardiovascular outcomes. Approximately one half of patients with hypertension adhere to prescribed medications, and fewer than one in three patients have controlled blood pressure.
Several recent studies have highlighted the importance of patient medication adherence and have outlined factors that affect patient compliance with prescribed therapy.
On the basis of published studies, a conceptual framework of factors that affect patient adherence is presented. Recognizing patient nonadherence to medical therapy as a factor leading to poor blood pressure control and adverse outcomes remains a key challenge for clinicians caring for patients with hypertension.
患者对抗高血压药物治疗方案的依从性是实现血压控制和降低不良心血管结局的一个复杂但重要的因素。大约一半的高血压患者坚持服用处方药，而血压得到控制的患者不到三分之一。
最近的几项研究强调了患者药物依从性的重要性，并概述了影响患者遵医嘱治疗的因素。
基于已发表的研究，提出了一个影响患者依从性的因素的概念框架。认识到患者不坚持药物治疗是导致血压控制不佳和不良结局的一个因素，对于照顾高血压患者的临床医生来说仍然是一个关键挑战。
