Gagnadoux F, Nguyen X L, Rakotonanahary D, Vidal S, Fleury B
Service de Pneumologie, Hôpital Saint-Antoine, Paris, France.
Eur Respir J. 2004 Jun;23(6):891-5. doi: 10.1183/09031936.04.00089604.
The aim of this study was to correlate daily use of nasal continuous positive airway pressure (nCPAP) with total sleep time (TST) evaluated by home actigraphy. Actigraphy was validated by comparing TST determined by actigraphy (aTST) and polysomnography (pTST) in 24 untreated patients with suspected sleep apnoea. The % sleep time spent under nCPAP was estimated on 3 consecutive days in 28 patients receiving long-term nCPAP, by comparing machine-use periods with sleep periods identified by home actigraphy. The mean difference between pTST and aTST was 2.5 min. The correlation coefficient between aTST and pTST was 0.90. Daily use of nCPAP over the 3 study days was 388 +/- 114 min. nCPAP was used 41-100% (82 +/- 17% (mean +/- sD)) of sleep time detected by actigraphy. Some patients used nCPAP during nonsleep periods. In conclusion, comparison of nasal continuous positive airway pressure use with sleep time estimated by home actigraphy shows marked individual differences in the % sleep time under nasal continuous positive airway pressure. These results suggest that actigraphic estimation of sleep time under nasal continuous positive airway pressure could provide a better index than simple daily use of the device to evaluate the impact of treatment in sleep apnoea.
本研究的目的是将鼻持续气道正压通气(nCPAP)的每日使用情况与通过家庭活动记录仪评估的总睡眠时间(TST)相关联。通过比较24名未经治疗的疑似睡眠呼吸暂停患者的活动记录仪测定的TST(aTST)和多导睡眠图(pTST)来验证活动记录仪。通过将机器使用时间与家庭活动记录仪确定的睡眠时间进行比较,对28名接受长期nCPAP治疗的患者连续3天估计nCPAP治疗下的睡眠时间百分比。pTST和aTST之间的平均差异为2.5分钟。aTST和pTST之间的相关系数为0.90。在3个研究日中,nCPAP的每日使用时间为388±114分钟。nCPAP的使用时间占活动记录仪检测到的睡眠时间的41%-100%(平均±标准差为82±17%)。一些患者在非睡眠时间使用nCPAP。总之,将鼻持续气道正压通气的使用情况与家庭活动记录仪估计的睡眠时间进行比较,结果显示在鼻持续气道正压通气治疗下的睡眠时间百分比存在显著个体差异。这些结果表明,通过活动记录仪估计鼻持续气道正压通气治疗下的睡眠时间,可能比单纯每日使用该设备能更好地评估睡眠呼吸暂停治疗的效果。