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对15例顽固性腹水肝硬化患者进行自发性透析超滤并腹腔内回输浓缩液。

Spontaneous dialytic ultrafiltration with intraperitoneal reinfusion of the concentrate in 15 cirrhotic patients with intractable ascites.

作者信息

Cadranel J F, Grippon P, Gargot D, Lunel F, Bernard B, Valla D, Opolon P

机构信息

Service d'Hépato-Gastro-Entérologie, Hopital de la Salpétrière, Paris, France.

出版信息

Int J Artif Organs. 1992 Mar;15(3):168-71.

PMID:1521902
Abstract

The clinical efficacy and tolerance of dialytic ultrafiltration of ascites through a hemofilter (DUF) with peritoneal reinfusion of the concentrate was evaluated in 15 cirrhotic patients with intractable ascites. All together, 51 DUF procedures were carried out. An average of 8.6 was ultrafiltered during 12 h with no significant change in blood pressure, hemoglobin, coagulation parameters or plasma creatinine. A significant increase in ascitic protein concentration was observed immediately after the procedure and a slight but significant increase in 24 h urinary output. A controlled evaluation of DUF compared to large paracenteses seems to be justified by these preliminary results.

摘要

对15例肝硬化顽固性腹水患者评估了通过血液滤过器进行腹水透析超滤(DUF)并将浓缩液回输至腹膜的临床疗效及耐受性。共进行了51次DUF操作。12小时内平均超滤量为8.6,血压、血红蛋白、凝血参数或血浆肌酐无显著变化。操作后即刻观察到腹水蛋白浓度显著升高,24小时尿量轻微但显著增加。这些初步结果似乎证明对DUF与大量腹腔穿刺放液进行对照评估是合理的。

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