多特异性有机阳离子转运体：其功能及与药物的相互作用 - Suppr

Suppr

超能文献

Polyspecific organic cation transporters: their functions and interactions with drugs.

作者信息

Koepsell Hermann

机构信息

Institute of Anatomy und Cell Biology, University Würzburg, Koellikerstrasse 6, 97070 Würzburg, Germany.

出版信息

Trends Pharmacol Sci. 2004 Jul;25(7):375-81. doi: 10.1016/j.tips.2004.05.005.

DOI:10.1016/j.tips.2004.05.005

PMID:15219980

Abstract

摘要

相似文献

Polyspecific organic cation transporters: their functions and interactions with drugs.多特异性有机阳离子转运体：其功能及与药物的相互作用

Trends Pharmacol Sci. 2004 Jul;25(7):375-81. doi: 10.1016/j.tips.2004.05.005.

Role of organic cation transporters in drug-induced toxicity.有机阳离子转运体在药物诱导毒性中的作用。

Expert Opin Drug Metab Toxicol. 2011 Feb;7(2):159-74. doi: 10.1517/17425255.2011.547474.

The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations.MATE蛋白作为代谢性和外源性有机阳离子的基本转运体。

Trends Pharmacol Sci. 2006 Nov;27(11):587-93. doi: 10.1016/j.tips.2006.09.001. Epub 2006 Sep 25.

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications.多特异性有机阳离子转运体：结构、功能、生理作用及生物制药意义

Pharm Res. 2007 Jul;24(7):1227-51. doi: 10.1007/s11095-007-9254-z. Epub 2007 May 1.

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy.有机阳离子转运体（OCTs、MATEs），药物治疗重要性的体外和体内证据。

Handb Exp Pharmacol. 2011(201):105-67. doi: 10.1007/978-3-642-14541-4_3.

Physiological and pharmacokinetic roles of H+/organic cation antiporters (MATE/SLC47A).H⁺/有机阳离子反向转运体（MATE/SLC47A）的生理和药代动力学作用

Biochem Pharmacol. 2008 May 1;75(9):1689-96. doi: 10.1016/j.bcp.2007.12.008. Epub 2007 Dec 27.

[Identification, structure and function of a drug transporter at the final step of extrusion].

Tanpakushitsu Kakusan Koso. 2008 Jan;53(1):52-8.

Regulation of drug transporters by PDZ adaptor proteins and nuclear receptors.PDZ衔接蛋白和核受体对药物转运体的调控

Eur J Pharm Sci. 2006 Apr;27(5):487-500. doi: 10.1016/j.ejps.2005.11.006. Epub 2006 Jan 11.

Substrate recognition and translocation by polyspecific organic cation transporters.多特异性有机阳离子转运体的底物识别和转运。

Biol Chem. 2011 Jan;392(1-2):95-101. doi: 10.1515/BC.2011.009.

Role of organic cation transporters in the renal handling of therapeutic agents and xenobiotics.有机阳离子转运体在治疗药物和外源性物质肾脏处理中的作用。

Toxicol Appl Pharmacol. 2005 May 1;204(3):309-19. doi: 10.1016/j.taap.2004.10.021.

引用本文的文献

Influence of OCT2 gene variants on metformin efficacy in type 2 diabetes: insights into pharmacogenomics and drug interactions.OCT2基因变异对2型糖尿病患者二甲双胍疗效的影响：药物基因组学与药物相互作用的见解

J Transl Med. 2025 Aug 7;23(1):884. doi: 10.1186/s12967-025-06720-y.

The Role of Solute Carrier Transporters in Efficient Anticancer Drug Delivery and Therapy.溶质载体转运体在高效抗癌药物递送与治疗中的作用

Pharmaceutics. 2023 Jan 21;15(2):364. doi: 10.3390/pharmaceutics15020364.

Organelle-Selective Membrane Labeling through Phospholipase D-Mediated Transphosphatidylation.通过磷脂酶D介导的转磷脂酰基作用实现细胞器选择性膜标记

JACS Au. 2022 Nov 28;2(12):2703-2713. doi: 10.1021/jacsau.2c00419. eCollection 2022 Dec 26.

Imaging and Editing the Phospholipidome.磷脂组学的成像与编辑

Acc Chem Res. 2022 Nov 1;55(21):3088-3098. doi: 10.1021/acs.accounts.2c00510. Epub 2022 Oct 24.

Current Chemical, Biological, and Physiological Views in the Development of Successful Brain-Targeted Pharmaceutics.当前在成功的脑靶向药物制剂开发中的化学、生物学和生理学观点。

Neurotherapeutics. 2022 Apr;19(3):942-976. doi: 10.1007/s13311-022-01228-5. Epub 2022 Apr 7.

Drug Metab Dispos. 2022 Feb 22;50(9):1218-27. doi: 10.1124/dmd.121.000707.

Analysis of OCT1, OCT2 and OCT3 gene polymorphisms among Type 2 diabetes mellitus subjects in Indian ethnicity, Malaysia.印度裔马来西亚2型糖尿病患者中OCT1、OCT2和OCT3基因多态性分析

Saudi J Biol Sci. 2022 Jan;29(1):453-459. doi: 10.1016/j.sjbs.2021.09.008. Epub 2021 Sep 14.

Mollusc-Derived Brominated Indoles for the Selective Inhibition of Cyclooxygenase: A Computational Expedition.基于软体动物源溴代吲哚类化合物的环氧化酶选择性抑制作用：计算研究。

Molecules. 2021 Oct 29;26(21):6538. doi: 10.3390/molecules26216538.

Inhibition of the Hepatic Uptake of Tc-Tetrofosmin Using an Organic Cation Transporter Blocker.使用有机阳离子转运体阻滞剂抑制肝脏对锝-替曲膦的摄取。

Pharmaceutics. 2021 Jul 13;13(7):1073. doi: 10.3390/pharmaceutics13071073.

Mechanisms Involved in Ototoxicity.耳毒性的相关机制。

Semin Hear. 2011 Aug;32(3):217-228. doi: 10.1055/s-0031-1286616.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验