一种与艾滋病相关的支原体——隐匿支原体的精氨酸脱氨酶基因。

Arginine deiminase gene of an AIDS-associated mycoplasma, Mycoplasma incognitus.

作者信息

Sugimura K, Ohno T, Kimura Y, Kimura T, Azuma I

机构信息

Institute of Immunological Science, Hokkaido University, Japan.

出版信息

Microbiol Immunol. 1992;36(6):667-70. doi: 10.1111/j.1348-0421.1992.tb02069.x.

DOI:10.1111/j.1348-0421.1992.tb02069.x

PMID:1522818

Abstract

Recently, we have demonstrated by molecular cloning that a strong immunosuppressive factor derived from Mycoplasma arginini is arginine deiminase. We show here that mycoplasma species identified in many of AIDS patients also bear the arginine deiminase gene. The implication of the arginine deiminase gene detected in AIDS-associated mycoplasma species is discussed.

摘要

最近，我们通过分子克隆证明，源自精氨酸支原体的一种强效免疫抑制因子是精氨酸脱亚氨酶。我们在此表明，在许多艾滋病患者体内鉴定出的支原体物种也携带精氨酸脱亚氨酶基因。本文讨论了在与艾滋病相关的支原体物种中检测到的精氨酸脱亚氨酶基因的意义。