Leonhardt W, Hanefeld M, Haller H
Int J Obes. 1978;2(1):33-45.
The volume of isolated adipocytes in specimens from the subcutis of the abdomen was measured using the pulse counter technique. The lipid content was determined as esterified fatty acids.
(1). Adipocyte enlargement is mainly caused by lipid deposition, despite a slight increase in the lipid free volume. (2). Two cell populations were detected in some cases, with the smaller fraction having a volume between 0.024 and 0.129 nl, which is lower than the common range for human adipocytes. (3). An analysis of large numbers of cells in single specimens revealed the lognormal type to fit the volume distribution better than the normal type. (4). Standard deviations of the lognormal distributions decrease with the mean cell volumes. Calculation by extrapolation shows the maximum adipocyte volume is of the order of 1 nl. (5). Normal curves of the adipocyte volume vs body weight index were set up for 142 test persons. They approach maximum volumes and differ with sex. (6). The normal adipocyte volume is ideal weight persons without metabolic disease is in the order of 0.3 nl.
使用脉冲计数器技术测量腹部皮下组织标本中分离出的脂肪细胞体积。脂质含量以酯化脂肪酸测定。
（1）。尽管无脂体积略有增加，但脂肪细胞增大主要由脂质沉积引起。（2）。在某些情况下检测到两个细胞群体，较小部分的体积在0.024至0.129 nl之间，低于人类脂肪细胞的常见范围。（3）。对单个标本中大量细胞的分析表明，对数正态类型比正态类型更适合体积分布。（4）。对数正态分布的标准差随平均细胞体积减小。外推计算表明最大脂肪细胞体积约为1 nl。（5）。为142名测试者建立了脂肪细胞体积与体重指数的正态曲线。它们接近最大体积且因性别而异。（6）。无代谢疾病的理想体重者的正常脂肪细胞体积约为0.3 nl。
