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If the "adaptive" immune system can recognize a significant portion of the pathogenic universe to which the "innate" immune system is blind, then..

作者信息

Cohn M

机构信息

Conceptual Immunology Group, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

出版信息

Scand J Immunol. 2004 Jul-Aug;60(1-2):1-2. doi: 10.1111/j.0300-9475.2004.01449.x.

Abstract

The "adaptive" immune repertoire functionally recognizes pathogens (and their toxic products) that the "innate" defense system misses. This requires that the self-nonself discrimination and the regulation of effector output be dependent primarily on somatic learning mechanisms (i.e. on the somatically generated, large, random "adaptive" immune paratopes repertoire).

摘要

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