Zhao Qin-Ping, Moon Sung-Ung, Lee Hyeong-Woo, Na Byoung-Kuk, Cho Seung-Yull, Kong Yoon, Jiang Ming-Sen, Li Ai-Hua, Kim Tong-Soo
Department of Tropical and Endemic Parasitic Diseases, National Institute of Health, Seoul 122-701, Korea.
Clin Diagn Lab Immunol. 2004 Jul;11(4):814-7. doi: 10.1128/CDLI.11.4.814-817.2004.
The diagnostic applicability of the Clonorchis sinensis recombinant 7-kDa protein was evaluated. In enzyme-linked immunosorbent assays and immunoblots, the protein showed high sensitivities (81.3 and 71.9%, respectively) and specificities (92.6 and 89.7%, respectively) for sera obtained from various helminthic infections. Some paragonimiasis sera showed cross-reactions. The antigen might be valuable in the serodiagnosis of human clonorchiasis.
评估了华支睾吸虫重组7-kDa蛋白的诊断适用性。在酶联免疫吸附测定和免疫印迹中,该蛋白对从各种蠕虫感染获得的血清显示出高敏感性(分别为81.3%和71.9%)和特异性(分别为92.6%和89.7%)。一些肺吸虫病血清显示出交叉反应。该抗原可能在人类华支睾吸虫病的血清诊断中有价值。