Steffen Charles
Am J Dermatopathol. 2004 Aug;26(4):334-41. doi: 10.1097/00000372-200408000-00009.
In 1948, Lauren V. Ackerman described a neoplasm of the oral mucous membrane, which he thought represented a unique type of squamous cell carcinoma and that is now termed verrucous carcinoma of Ackerman. "Verrucous carcinoma" has also been used as a generic term under which are placed giant condyloma of Buschke-Loewenstein and carcinoma cuniculatum. This report will synopsize the life of Lauren Vedder Ackerman, review the original and subsequent report by Ackerman, and discuss some other reports of oral verrucous carcinoma. Because this review is directed to histopathologists, the histopathology will be emphasized. Other aspects of the neoplasm (eg, clinical picture, incidence, etiopathogenesis, and treatment) will not be discussed, or if so, only briefly. Giant condyloma acuminatum of Buschke-Loewenstein and carcinoma cuniculatum and studies that mention the occurrence of Ackerman's verrucous carcinoma in the pharynx, larynx, and esophagus will be mentioned only in the section on classification.
1948年,劳伦·V·阿克曼描述了一种口腔黏膜肿瘤,他认为这是一种独特类型的鳞状细胞癌,现在被称为阿克曼疣状癌。“疣状癌”也被用作一个通用术语,其中包括Buschke-Loewenstein巨大尖锐湿疣和漏斗状癌。本报告将简述劳伦·维德·阿克曼的生平,回顾阿克曼的原始报告及后续报告,并讨论其他一些口腔疣状癌的报告。由于本综述针对组织病理学家,将重点强调组织病理学。肿瘤的其他方面(如临床表现、发病率、病因发病机制和治疗)将不作讨论,或仅作简要讨论。Buschke-Loewenstein巨大尖锐湿疣和漏斗状癌以及提及阿克曼疣状癌在咽、喉和食管中发生情况的研究将仅在分类部分提及。