Spiro R H
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Am J Surg. 1998 Nov;176(5):393-7. doi: 10.1016/s0002-9610(98)00232-3.
The salient clinical and pathological features of verrucous carcinoma, as first described by Ackerman in 1948, are reviewed. Two case reports are presented. The first concerns a personal experience with a patient who had five surgical procedures for multifocal oral verrucous carcinoma and remains alive and well 28 years after her initial treatment. The second report highlights the remarkable story of President Grover Cleveland's secret surgery for verrucous carcinoma of the palate in 1893. Current concepts about the management of this uncommon tumor are reviewed, as well as some recent investigations that deal with its etiology.
本文回顾了1948年阿克曼首次描述的疣状癌显著的临床和病理特征。文中给出了两例病例报告。第一例是作者个人经历，一名患者因多灶性口腔疣状癌接受了五次外科手术，初始治疗28年后仍健在且状况良好。第二例报告讲述了1893年格罗弗·克利夫兰总统因腭部疣状癌接受秘密手术的传奇故事。本文还回顾了关于这种罕见肿瘤治疗的当前理念，以及一些有关其病因的最新研究。
