Lewis James S
Department of Pathology and Immunology, Division of Anatomic and Molecular Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Head Neck Pathol. 2011 Mar;5(1):23-30. doi: 10.1007/s12105-010-0232-0. Epub 2010 Dec 17.
Although squamous cell carcinoma (SCC) variants account for less than 10% of all laryngeal SCCs, they have many unique biological, morphological, and clinical features. They are also easily confused with other tumor types. Recognition of them is critical for surgical pathologists as is the knowledge of what they mean for the patient. Three of the most common and important of these are basaloid, verrucous, and papillary SCC. These tumor types will be briefly reviewed with a focus on specific controversies, biological questions, and/or recent advancements in our understanding of them.
尽管鳞状细胞癌(SCC)变体在所有喉鳞状细胞癌中占比不到10%,但它们具有许多独特的生物学、形态学和临床特征。它们也很容易与其他肿瘤类型混淆。对手术病理学家来说,识别它们至关重要,了解它们对患者的意义也同样重要。其中三种最常见且重要的是基底样、疣状和乳头状鳞状细胞癌。将简要回顾这些肿瘤类型,重点关注特定的争议、生物学问题和/或我们对它们理解的最新进展。