Seedat Soraya, Pienaar Willem P, Williams David, Stein Daniel J
Medical Research Council Unit on Anxiety and Stress Disorders, Department of Psychiatry, University of Stellenbosch, PO Box 19063, Tygerberg, Cape Town 7505, South Africa.
Curr Psychiatry Rep. 2004 Aug;6(4):262-7. doi: 10.1007/s11920-004-0075-z.
Essential elements of all research include balance of risks and benefits, unbiased selection of research samples, and assurance of the rights of individual participants. This paper highlights some key ethical issues and summarizes recent evidence relating to participation in, and conduct of, trauma-focused studies with special reference to vulnerable populations (eg, women and children, refugees, survivors of human rights violations, and survivors of trauma in the developing world). A concise ethical framework, rather than rigid guidelines (that may not be applicable to all trauma studies), may be a more useful point of reference for investigators and ethics committees or institutional review boards. Despite the increased empiric data available to inform ethical dilemmas regarding trauma research, more cost-burden analysis research in varying trauma populations and careful investigation of factors that contribute to risk and benefit is required.
所有研究的基本要素包括风险与收益的平衡、研究样本的无偏选择以及对个体参与者权利的保障。本文重点介绍了一些关键的伦理问题，并总结了近期有关参与和开展以创伤为重点的研究的证据，特别提及了弱势群体（如妇女和儿童、难民、人权侵犯幸存者以及发展中世界的创伤幸存者）。一个简洁的伦理框架，而非严格的指导方针（可能并不适用于所有创伤研究），可能对研究人员以及伦理委员会或机构审查委员会来说是更有用的参考点。尽管有更多实证数据可用于解决创伤研究中的伦理困境，但仍需要对不同创伤人群进行更多成本负担分析研究，并仔细调查导致风险和收益的因素。
