Wang C-J, Yen C-F, Lee C-L, Tashi T, Soong Y-K
Department of Obstetrics and Gynecology, Division of Gynecologic Endoscopy, Chang Gung Memorial Hospital, Linkou Medical Center, Kwei-Shan, Tao-Yuan, Taiwan.
Eur J Obstet Gynecol Reprod Biol. 2004 Aug 10;115(2):219-23. doi: 10.1016/j.ejogrb.2003.12.021.
To examine the safety and feasibility of laparoscopically assisted vaginal hysterectomy (LAVH) for uteri weighing 500 g or more as compared to uteri weighing less than 500 g in the management of benign gynecological diseases.
In this prospective comparative study, 189 women with different benign gynecological diseases were scheduled for laparoscopically assisted vaginal hysterectomy. They were divided into two groups, with uterine weight greater than 500 g and uterine weight less than 500 g. Outcome measures for both the groups were studied comparatively in terms of length of operative time, amount of blood loss, requirement of blood transfusion and length of hospital stay.
Length of operation and amount blood loss were significantly greater in the uteri >o r = 500 g group than in the <500 g at 91.1 +/- 28.7 min versus 77.4 +/- 26.6 min (P < 0.01), and 570.5 +/- 503.6 ml versus 262.5 +/- 270.0 ml (P < 0.001), respectively. However, there was no difference in length of hospital stay and overall incidence of operative complications between the two groups. None of the women had any major complications though 17 minor complications were noted. There was no incidence of switching to abdominal laparatomy during the operation except for one patient who required "minilaparotomy" for removal of large surgical specimen (2400 g). Extreme intra-operative hemorrhage of more than 1000 ml occurred in five patients, however, they made full recovery after blood transfusion. Rate of blood transfusion was significantly lower in the uteri <500 g group (4.8% versus 34.9%, (P < 0.001).
This study demonstrates that despite the increased operating time and blood loss, LAVH can be safely performed for large uterus. However, surgeons need to be aware of the high risk of blood transfusion in these patients.
探讨在良性妇科疾病治疗中,腹腔镜辅助阴式子宫切除术(LAVH)用于切除重量500g及以上子宫与重量小于500g子宫的安全性及可行性。
在这项前瞻性对照研究中,189例患有不同良性妇科疾病的女性计划接受腹腔镜辅助阴式子宫切除术。她们被分为两组,子宫重量大于500g组和子宫重量小于500g组。对两组的手术时间、失血量、输血需求及住院时间等结局指标进行比较研究。
子宫重量≥500g组的手术时间和失血量显著多于<500g组,分别为91.1±28.7分钟对77.4±26.6分钟(P<0.01),以及570.5±503.6ml对262.5±270.0ml(P<0.001)。然而,两组的住院时间及手术并发症总发生率并无差异。尽管记录到17例轻微并发症,但无一例女性发生任何严重并发症。手术过程中除1例因需“小剖腹术”切除巨大手术标本(2400g)外,无中转开腹情况。5例患者术中发生超过1000ml的严重出血,不过输血后均完全康复。子宫重量<500g组的输血率显著更低(4.8%对34.9%,P<0.001)。
本研究表明,尽管手术时间延长和失血量增加,但LAVH可安全用于切除大子宫。然而,外科医生需意识到这些患者输血风险较高。