Sesti Francesco, Ruggeri Velia, Pietropolli Adalgisa, Piccione Emilio
Section of Gynaecology and Obstetrics, Department of Surgery, School of Medicine, Tor Vergata University Hospital, Viale Oxford 81, Rome, Italy.
JSLS. 2008 Jul-Sep;12(3):246-51.
To compare the surgical and immediate postoperative outcomes for vaginal hysterectomy (VH) with those for laparoscopically assisted vaginal hysterectomy (LAVH) in patients with enlarged myomatous uterus.
Eighty women requiring hysterectomy for an enlarged myomatous uterus were randomly allocated into 2 treatment arms: VH (n=40) and LAVH (n=40). The randomization procedure was based on a computer-generated list. The primary outcome was a comparison of the discharge times between the 2 procedures. Continuous outcome variables were analyzed using the Student t test. Discrete variables were analyzed with the chi-square test or Fisher's exact test. P<0.05 was considered statistically significant.
The mean discharge time was longer for LAVH than for VH (72+/-4.2 vs 48+/-2.6 h; P=0.00). VH resulted in shorter times for paralytic ileus (19+/-3 vs 26+/-3 h; P=0.00) and surgery (71+/-3 vs 129+/-7 min; P=0.00). The intraoperative blood loss was less with VH (186.0+/-52 vs 362.7+/-65 mL; P=0.00). No intraoperative complications occurred, and no patient was returned to the operative theater in either group.
Several surgical and immediate postoperative outcomes were significantly better in the VH group than in the LAVH group. However, further controlled prospective studies are required for identifying the best approach for hysterectomy in patients with enlarged uterus.
比较子宫肌层增厚患者行阴道子宫切除术(VH)与腹腔镜辅助阴道子宫切除术(LAVH)的手术及术后即刻效果。
80例因子宫肌层增厚需行子宫切除术的女性被随机分为两组:VH组(n = 40)和LAVH组(n = 40)。随机分组程序基于计算机生成的列表。主要结局是比较两种手术的出院时间。连续结局变量采用Student t检验进行分析。离散变量采用卡方检验或Fisher精确检验进行分析。P < 0.05被认为具有统计学意义。
LAVH组的平均出院时间比VH组长(72±4.2对48±2.6小时;P = 0.00)。VH导致麻痹性肠梗阻时间(19±3对26±3小时;P = 0.00)和手术时间(71±3对129±7分钟;P = 0.00)更短。VH的术中失血量更少(186.0±52对362.7±65毫升;P = 0.00)。两组均未发生术中并发症,也没有患者返回手术室。
VH组的一些手术及术后即刻效果明显优于LAVH组。然而,需要进一步的对照前瞻性研究来确定子宫增大患者子宫切除术的最佳方法。